IV Geant4 International User Conference at the physics-medicine-biology frontier
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Europe/Rome
Centro Congressi “Federico II”, (Napoli, Italy)
Centro Congressi “Federico II”,
Napoli, Italy
Via Partenope 36, Napoli, Italy
Giovanni Mettivier
Description
Developers and users of Monte Carlo techniques applied to Medicine in the clinic, industry and academy, are invited to participate to the Fourth Geant4 International User Conference 2022 for presenting, discussing and exchanging information on the scientific and technical innovations in application areas including medical radiation sources, radiation therapy treatment planning in conventional and in particle therapy, brachytherapy, radiation dosimetry, radiation shielding, radiation imaging, nuclear medicine and radiobiology. Connections with technology of inverse optimization, deformable image registration, machine learning techniques, parallel and GPU computing, are also topics of interest.
Topics
- Imaging
- Radiotherapy treatments
- Protontherapy
- Hadrontherapy
- Radiobiology, including Geant4-DNA
- Radiation Protection
- Detector development
- Computing
Registration
Registration Form
Participants
Adil Bardane
Aimee McNamara
Alaa Barhoum
Aleksandra Ristic Fira
Alexei Sytov
Alexis Pereda
Andreas Resch
Angelo Taibi
Anh Le Tuan
Anna Selva
Antonio Sarno
Antonio Stefano Italiano
Asma TOUIL
Asra Sadat Talebi
Azam Zabihi
azam zabihi
Bastien DOIGNIES
Behcet Alpat
Bert Julien
Brad Oborn
Carmen Villagrasa
Ceferino Obcemea
Ceferino Obcemea
Celebrity Groenendijk
Christian Finck
Christina Zacharatou
Chundi Fan
Daniele Esposito
Daniele Pistone
David Bolst
David Sarrut
Dousatsu Sakata
El Ghalbzouri Tarik
Enas Moustafa
ernesto tan
Fateme Farokhi
Francesca Maddaloni
Francesca Nicolanti
Francesco Romano
Gabriele Parisi
Gaëtan Raymond
Giada Petringa
Gianfranco Paternò
Giovanna Tramontin Carneiro
Giovanni Di Domenico
Giovanni Mettivier
Giuliana Milluzzo
Giuseppe Cirrone
Ioanna Kyriakou
Ioannis Sechopoulos
Ivan Petrovic
Jacopo Magini
Jake Harold Pensavalle
Jawaher AL-TUWEITY
Jay Archer
Jenny Spiga
Jeremy Brown
José Manuel Quesada Molina
Julien Bordes
Kilian-Simon Baumann
Klaudiusz Jakubowski
Larissa Derksen
Laura Antonia Cerbone
Laura Ballisat
Lorenzo Arsini
Loïc Grevillot
Lydia Maigne
Mahmoud Alabsy
Maikol Salas Ramirez
Marc Granado-Gonzalez
Marie Vanstalle
Marine HERVE
Mario A. Bernal
Marissa Kielly
Martina Favaretto
Matthew Large
Maxim Lobok
Miguel Antonio Cortes-Giraldo
Mikhail Rumiantcev
Milos Dordevic
MOHAMMED YJJOU
Morad El Kafhali
Natalia Chamorro Claver
Nicola Ferrara
Nikolay Dukov
Nina McWilliams
Olga Kochebina
Panagiotis Papadimitroulas
Paolo Cardarelli
Pedro Arce
SABRINA LORENA PORINI
Sara ZEIN
Sebastien Incerti
Shubhangi Makkar
Sofia KOLOVI
Susanna Guatelli
Théo KAPRELIAN
Tobias Meißner
Valentina Paneta
VARVARA LAGAKI
VERDERI Marc
Victor Levrague
Vladimir Ivantchenko
Xingyu Lu
Yacine Elattaoui
Yann PERROT
Yann Thibaut
Zahra Ahmadi Ganjeh
Zhivko Bliznakov
Prof. Giovanni Mettivier, PhD
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Registration
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Opening Session
Chairs: Susanna Guatelli (AU), Sebastien Incerti (F), Jeremy Brown (AU) and Giovanni Mettivier (IT)
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1
Geant4 Medical Physycs Application in Naples (A. Sarno)Speaker: Dr Antonio Sarno (Dipartimento di Fisica E. Pancini UNINA and INFN Napoli)
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2
Keynote Lecture: Recent Geant4 developmentsSpeaker: Prof. Marc Vederi (CNRS (Laboratoire Leprince-Ringuet: LLR))
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3
Development of interaction models in Geant4- DNA to simulate cosmic rays’ effects on ionmolecules reaction in the atmosphereSpeaker: Francesca Nicolanti (Istituto Nazionale di Fisica Nucleare)
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4
Nanodosimetric Study of Radiation in the Brain and Eyes of Astronauts on the Lunar SurfaceSpeaker: Jay Archer (Centre for Medical Radiation Physics, University of Wollongong)
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5
Calculation of organ-specific radiation quality factors for the radioprotection of astronauts on the Moon: a microdosimetric approachSpeaker: Matthew Large (University of Wollongong)
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6
GEANT4-Gamma Diffraction Code Based on Laue lens Modelling: Design Foundation and Implementation of the First Set of Models in GEANT4Speaker: Alaa Barhoum (UNSW)
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7
Geant4 simulations of two types of CdZnTe-based γ-ray spectrometers for the monitoring of the radioactivity in the marine environmentSpeaker: VARVARA LAGAKI (National Kapodistrian University of Athens)
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1
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10:30
Coffee Break
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Geant4 for Medical Physics
Chairs: Giada Petringa (I) and Laurent Desorgher (CH)
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8
Keynote: Update on the G4-Med project and on the Geant4 Advanced Examples for medical applicationsSpeaker: Susanna Guatelli (Centre For Medical Radiation Physics, University of Wollongong)
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9
Keynote: Geant4 applications in MRI-guided x-ray and proton beam therapySpeaker: B. M. Oborn (Illawarra Cancer Care Centre, Wollongong Hospital, NSW 2500 Australia)
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10
Performance evaluation of Siemens Somatom go.Open Pro CT scanner using GATE: dosimetry and image quality for treatment planning in radiotherapySpeaker: Gaëtan Raymond (in2p3 France)
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11
Recent developments of Geant4 Advanced Examples for medical applicationsSpeaker: Francesco Romano (INFN - Catania Section)
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12
Noise in accelerated in-silico x-ray breast images: impact on the breast anatomy and the detectorSpeaker: Dr Antonio Sarno (University of Naples, Dept. of Physics “Ettore Pancini”, & INFN, Naples, Italy)
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13
Geant4 Monte Carlo simulations for size specific organ dose estimates in CT based on patient silhouette and voxelilzed phantoms.Speaker: Francesca Saveria Maddaloni (Department of Physics “Ettore Pancini” Università di Napoli Federico II & INFN Napoli, Napoli (Italy))
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14
Generation and tracking of inverse Compton scattering photons in Geant4Speaker: Gianfranco Paternò (Istituto Nazionale di Fisica Nucleare)
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15
A Geant4 tool for the simulation of contrast enhanced dual-energy mammography – Study of polychromatic versus quasi-monochromatic X- ray spectra and different contrast agentsSpeaker: Dr Gianfranco Paternò (Istituto Nazionale di Fisica Nucleare)
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8
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13:00
Lunch
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Geant4 and Artificial Intelligence
Chairs: David Sarrut (F) and Gianfranco Paternò (IT)
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16
Keynote: Artificial Intelligence for Monte Carlo Simulation in Medical PhysicsSpeaker: David Sarrut (CNRS and at CREATIS / Léon Bérard cancer center)
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17
CNN for multi-proton events at the ASTRA range telescope for pCTSpeaker: Marc Granado-Gonzalez (School of physics and astrophysics, University of Birmingham, Birmingham, United Kingdom)
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18
FAST EMULATION OF DEPOSITED DOSE DISTRIBUTIONS BY MEANS OF DEEP LEARNINGSpeaker: Lorenzo Arsini (Department of Physics, University of Rome “La Sapienza” and INFN)
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19
Towards the emulation of BLOB, a nuclear interaction model, with Deep LearningSpeaker: Lorenzo Arsini (Sapienza and INFN Sec. of Rome)
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20
Toward a generic approach for dose distribution recovery by using Deep Learning and GPU-based Geant4 simulationsSpeaker: Asma TOUIL (Laboratory of Medical Information Processing (LaTIM), INSERM-UMR 1101, Brest, (France))
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16
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Geant4 for Protrons and Hadrons Radiotherapy 1
Chairs: Lydia Maigne (F) and Loic Grevillot (CH)
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21
Keynote: Hadronic aspects in Geant4Speaker: José Manuel Quesada (University of Sevilla)
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22
4He dose- and track-averaged Linear Energy Transfer: Monte Carlo algorithms and experimental verificationSpeaker: Giada Petringa (Istituto Nazionale di Fisica Nucleare)
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23
Monte Carlo-based benchmark of a method for proton energy spectra reconstruction using radiochromic filmsSpeaker: Giuliana Giuseppina Milluzzo (Istituto Nazionale di Fisica Nucleare)
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24
On the need of using MC Simulations to optimize the design of a clonogenic assay to measure RBE as a function of LET and minimize the measurement uncertainty.Speaker: Natalia Chamorro Claver (CIEMAT)
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21
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16:18
Coffee Break
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Geant4 for Protrons and Hadrons Radiotherapy 2
Chairs: Cristina Zacharatou (IE) and Miguel Antonio Cortés-Giraldo (ES)
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25
Keynote Lecture: Geant4 for Hadron therapy: status and challengesSpeaker: Giada Petringa (Istituto Nazionale di Fisica Nucleare)
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26
Benchmarking GATE/Geant4 and RayStation MC for pencil beam scanning light ion beams in combination with a passive beam collimation for small fieldsSpeaker: Dr Andreas Resch (Medical University of Vienna)
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27
Benchmarking dose-averaged LET calculation of a commercial treatment planning system and GATE/Geant4 for carbon ion beamsSpeaker: Andreas Resch (Medical University of Vienna)
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28
IDEAL/GATE-RTion for independent dose calculation in carbon ion beam therapySpeaker: Dr Andreas Resch (MedAustron Ion Therapy Centre)
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29
Development of a Geant4 simulation platform of the HollandPTC R&D proton beamline for radiobiological studiesSpeaker: Celebrity Groenendijk (Radiation Science & Technology, Technical University Delft, Delft, the Netherlands)
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30
A review of Monte Carlo calculated fQ factors for ionization chambers in clinical proton beamsSpeaker: Dr Kilian-Simon Baumann (Department of Radiotherapy and Radiooncology, University Medical Center, Marburg, Germany)
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31
Using an iterative shielding approach for the first carbon ion therapy facility in the US by means of Geant4Speaker: David Bolst (University of Wollongong)
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32
Validation of Geant4 fragmentation models in 4He ion therapySpeaker: David Bolst (University of Wollongong)
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33
Biological dose estimation for proton and carbon ion treatment plans using the GATE platformSpeaker: Lydia Maigne (Laboratoire de Physique de Clermont, CNRS/IN2P3, Université Clermont Auvergne, Aubière, France)
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34
The new “RPWBA” implemented model for proton ionization and excitation of liquid water above 100 MeVSpeaker: Miguel Antonio Cortes-Giraldo (Universidad de Sevilla)
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25
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Tools based on Geant4
Chairs: Sebastien Incerti (F) and Pedro Arce (ES)
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35
Keynote Lecture: Status and Outlook of the TOPAS Tool for Particle SimulationSpeaker: Prof. Joseph Perl (SLAC National Accelerator Laboratory)
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36
Keynote: Recent developments in the TOPAS-nBio radiobiology toolkitSpeaker: Aimee McNamara (Harvard Medical School & Massachusetts General Hospital)
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37
Keynote Lecture: GATE AdvancesSpeaker: Prof. Lydia Maigne (Laboratoire de Physique de Clermont, CNRS/IN2P3, Université Clermont Auvergne, Aubière, France)
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38
Keynote: Latest developments in GAMOSSpeaker: Pedro Arce (CIEMAT)
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39
Keynote: Overview of the Geant4-DNA projectSpeaker: SEBASTIEN INCERTI (CNRS/IN2P3/CENBG)
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35
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10:30
Coffee Break
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Geant4 for Nuclear Medicine
Chairs: Jeremy Brown (AU) and Alexy Sytov (IT)
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40
Keynote: Monte Carlo for Nuclear Medicine: vision and future requirementsSpeaker: Prof. Ernesto Amato (BIOMORF Department, University of Messina, Messina, Italy and INFN Section of Catania, Catania, Italy)
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41
Investigating Quasi-Monte Carlo (QMC) methods for Geant4/Gate simulations in medical physicsSpeaker: Theo Kaprelian (Université de Lyon, CNRS, CREATIS, France)
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42
Cherenkov Luminescence Imaging of 90Y and nanoparticles loaded glass microspheresSpeaker: Asra Sadat Talebi (Department of medical physics, University of Tarbiat Modares, Tehran, Iran)
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43
The MC simulation of WIDMApp: an innovative approach for individual dose monitoring in Molecular RadiotherapySpeaker: Francesca Nicolanti (Sapienza and INFN Sec. of Rome)
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44
Monte Carlo simulations for the in-beam PETITION PET scannerSpeaker: Shubhangi Makkar (1. Center for Proton Therapy, PSI, Switzerland 2. Department of Physics, ETH Zürich, Switzerland)
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45
Quantum entanglement effects in Geant4 for PET applicationsSpeaker: Dr Julien Bordes (Department of Physics, University of York, York, UK)
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46
Calculation of Absorbed Dose Coefficients for Internal Ex Vivo Irradiation of Lymphocytes Using GATE and Geant4-DNASpeaker: Dr Maikol Salas Ramirez (Department of Nuclear medicine, University of Wuerzburg)
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47
Optimizing the design of a Timepix4 based compact gamma camera with validated Geant4 Monte Carlo simulationsSpeaker: Laura Antonia Cerbone (Dept. of Physics “Ettore Pancini”, University of Naples Federico II & INFN Naples, Naples (Italy).)
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40
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13:00
Lunch
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Geant4 for Nuclear Medicine
Chairs: Ernesto Amato (IT) and Jiulien Bordes (UK)
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48
A GATE in silico evaluation of the γ-eye preclinical system, for imaging alpha and beta radiopharmaceuticalsSpeaker: Dr Panagiotis Papadimitroulas (BIOEMTECH)
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49
Internal dosimetry of salivary glands in PSMA-targeted PET/CT: a Monte Carlo based studySpeaker: Dr Daniele Pistone (Università degli Studi di Messina, Dipartimento BIOMORF; INFN Sezione di Catania)
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50
Monte Carlo simulation for personalized dosimetry in radionuclide therapySpeaker: Giovanni Di Domenico (University of Ferrara and INFN)
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51
Internal bremsstrahlung: the missing process in beta decay Monte Carlo simulation for Dose-Point-Kernel estimationSpeaker: Dr Daniele Pistone (BIOMORF Department)
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52
Translating N-12 imaging to the clinic using Monte Carlo simulationsSpeaker: Zahra Ahmadi Ganjeh (Particle Therapy Research Center (PARTREC), Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands)
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53
Planar Coded Aperture Reconstruction for Gamma-Imaging via Machine Learning and the TOPAS Simulation toolkitSpeaker: T Meißner (Mannheim Institute for Intelligent Systems in Medicine (MIISM), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany)
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54
New Geant4 model of channeling in crystals and its potential applications in medical physicsSpeaker: Alexei Sytov (Istituto Nazionale di Fisica Nucleare)
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48
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15:30
Coffee Break
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Geant4 for Photons and Electrons Radiotheraphy: Geant for Photons and Electrons
Chairs: Aimee McNamara (USA) and Ioanna Kyriakou (GR)
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55
Keynote Lecture: Geant4 for Flash radiotherapy: status and challengesSpeaker: Prof. Laurent Desorgher (Lausanne University Hospital, Institute of radiation physics)
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56
Keynote: EM aspects in Geant4Speaker: Vladimir Ivanchenko (CERN, Geneva, Switzerland and Princeton University, USA)
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57
Extension of the discrete electron transport capabilities of the Geant4-DNA toolkit to the radiotherapeutic regimeSpeaker: Ioanna Kyriakou (Medical Physics Laboratory, Department of Medicine, University of Ioannina, Greece)
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58
Calculation of chemical species yields in liquid water after high energy electron irradiation up to 10 MeV using Geant4-DNASpeaker: Dr Sara Zein (Univ. Bordeaux, CNRS, LP2I Bordeaux)
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59
Validation of Monte Carlo GATE for IORTSpeaker: Giovanni Di Domenico (University of Ferrara and INFN)
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60
Evaluation of the effect of oxygen in Flash irradiation through Geant4-DNASpeaker: Fateme Farokhi (Istituto Nazionale di Fisica Nucleare)
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61
VALIDATED MONTE CARLO SIMULATION OF TRIODE- ELECTRON GUN EQUIPPED ELECTRONFLASH LINACSpeaker: Jake Harold Pensavalle (Istituto Nazionale di Fisica Nucleare)
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Monte Carlo optimization of the target configuration for bremsstrahlung x-ray production in flash radiotherapySpeaker: Paolo Russo (Dept. of Physics “Ettore Pancini”, University of Naples Federico II & INFN Naples, Naples (Italy).)
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63
Dose enhancement applied to synchrotron X-ray microbeams: computational modelling and experimental validation.Speaker: Dr Jon Duffy (University of Warwick)
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64
Development of Geant4 DICOM based dose calculation for Synchrotron Microbeam Radiation TherapySpeaker: Susanna Guatelli (Centre For Medical Radiation Physics, University of Wollongong)
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65
A Monte Carlo based investigation of the FLASH effect by examining inter-track interactions in radiobiological simulations performed with TOPAS-nBioSpeaker: Larissa Derksen (Institute of Medical Physics and Radiation Protection, University of Applied Sciences, Giessen, Germany)
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55
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Social Dinner
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Geant4 for DNA Demage evaluation
Chairs: Susanna Guatelli (AU) and Mario Bernal (BR)
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66
Keynote: DNA damage simulation and prediction of biological endpoints using Geant4-DNA - Development of molecularDNASpeaker: Dousatsu Sakata (Research Associate at National Institute of Radiological Sciences)
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67
MINAS TIRITH: a Geant4-DNA-based tool for modeling damage at the cell population scaleSpeaker: Yann Thibaut (IRSN/PSE-SANTE/SDOS/LDRI)
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Simulation of radio-induced DNA damages and their repair by means of Geant4-DNA Monte Carlo Track Structure codeSpeaker: Dr Yann Perrot (IRSN)
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69
Simulation and validation of plasmid DNA irradiation by electrons using Geant4-DNASpeaker: Dr Sara Zein (Univ. Bordeaux, CNRS, LP2I Bordeaux)
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70
Evaluation of dose rates and DNA damage on microorganisms living in naturally radioactive mineral springs using GATE and Geant4-DNASpeaker: Sofia Kolovi (Laboratory of Physics of Clermont, University of Clermont-Auvergne, CNRS/IN2P3, Aubiere, France)
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71
In-silico calculations of DNA damage induced by DaRT for a better understanding of the radiobiological effectiveness of this treatmentSpeaker: Laura Ballisat (School of Physics, University of Bristol, Bristol, UK)
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72
Monte Carlo simulations of microdosimetry and radiolytic species production for preclinical proton beam using GATE and Geant4-DNA as part of the FLASHMOD projectSpeaker: Lydia Maigne (Laboratoire de Physique de Clermont, CNRS/IN2P3, Université Clermont Auvergne, Aubière, France)
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73
A Geant4-DNA simulation of human cancer cells irradiated with helium ion beamsSpeaker: Milos Dordevic (Vinca Institute of Nuclear Sciences, National Institute of the Republic of Serbia, University of Belgrade)
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66
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10:20
Coffee Break
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Geant4 for microdosimetry
Chairs: Francesco Romano (IT) and David Bolst (AU)
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74
Estimation of energy imparted from ionization-based measurements at the nanometer scaleSpeaker: Dr Anna Selva (Istituto Nazionale di Fisica Nucleare)
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75
Impact of intracellular radionuclide distribution in Targeted Alpha Therapy : a Monte-Carlo biophysical study in 3D multicellular modelSpeaker: Victor Levrague (LPSC)
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76
Implementation of nitrogen cross-sections in Geant4-DNASpeaker: Dr Carmen Villagrasa (Institut de Radioprotection et de Sûreté Nucléaire (IRSN), Fontenay-Aux-Roses, France )
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77
Systematic uncertainty budget for a novel diamond microdosimeterSpeaker: Jacopo Magini (University of Surrey)
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78
First microdosimetric characterization of nuclear interaction events, and assessment of their effect on the dose-mean lineal energy uncertainty.Speaker: Gabriele Parisi (University of Surrey)
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Microdosimetry for proton treatment planningSpeaker: Jacopo Magini (University of Surrey)
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A new genome geometrical model with atomic resolution based on HiC-maps.Speaker: Mario A Bernal (Universidade Estadual de Campinas)
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74
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Geant4 for Neutrons and Space
Chairs: Carmen Villagrasa (F) and Jeremy Brown (AU)
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81
Neutron shielding strategies for dose quantification in Neutron Capture Enhanced Particle TherapySpeaker: Marissa Kielly (Centre for Medical Radiation Physics, University of Wollongong, Australia)
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82
High LET spectral and microdosimetric characterization of secondaries in the treatment of Alzheimer’s disease with Neutron Capture TherapySpeaker: Marine HERVE (1Institut de Radioprotection et de Sûreté Nucléaire (IRSN), Ionizing Radiation Dosimetry Laboratory (LDRI) Fontenay-aux-Roses, France)
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83
Development of a validated Monte Carlo model of the ACNS Dingo BeamlineSpeaker: Klaudiusz Jakubowski (University of Wollongong and Australian Nuclear Science and Technology Organisation, Australia)
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84
Matter RADiation interactions SIMulator for Space Applications (MRADSIM-Space)Speaker: Giovanni Bartolini (BEAMIDE srl, Perugia, Italy)
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81
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13:00
End of Workshop and V Geant4 International User Meeting announcement
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