In this tutorial I will briefly review the principles of synchrotron radiation, introduce the basics of tomographic microscopy and then showcase some of the latest imaging results, with particular focus on time-resolved experiments. I will then further discuss on how some of the tools originally designed for machine diagnostics purposes have developed into powerful, potentially game-changing...
The electron Bio-Imaging Centre (eBIC) is a UK national cryoEM facility located at the UK synchrotron Diamond Light Source. eBIC provides UK and international scientists with state-of-the-art experimental equipment, expertise, and training, in the field of cryo-electron microscopy, for single particle analysis, electron tomography, electron diffraction, and correlative microscopy. eBIC also...
Propagation-based X-ray phase-contrast tomography (XPCT) offers a unique potential to extend histology and pathohistology by a scalable, isotropic resolution without destructive slicing of the specimen and quantitative density-based contrast.
Here, we use virtual histology based on XPCT to image the human lung at synchrotron radiation endstations (P10, DESY) in different setups as well as...
The 3D complexity of biological tissues and intricate structural-functional connections call for state-of-the-art X-ray imaging approaches. Unlike other imaging techniques, X-ray phase-contrast tomography (XPCT) offers a highly sensitive 3D imaging approach to investigate different disease-relevant networks at levels ranging from the single cell through to the whole organ. We present here a...
