SIRR International Day: 2025 - Simulation and Biological Damage prediction

Monday 6 Oct 2025, 08:00 → 19:40 Europe/Rome

Aula Migneco (INFN-LNS)

Giada Petringa (Istituto Nazionale di Fisica Nucleare)

The Italian Society for Radiation Research (SIRR) is proud to announce the first international symposium it organizes, which will be held on October 6th, 2025, in Catania, Italy. This one-day event will focus on the prediction of biological damage through simulation, bringing together leading scientists working on Monte Carlo simulations, radiobiological modeling, and radiation-matter interaction.

The morning session will feature a series of invited talks by internationally recognized experts, including contributions on Geant4, Geant4-DNA, FLUKA, treatment planning systems, and the latest activities at ESA. In the afternoon, the symposium will be open to contributed presentations, offering the opportunity for young researchers and established scientists alike to share their latest findings and discuss open challenges in the field.

The abstract submission is now open, and we warmly invite the scientific community to participate actively in this exciting event.

08:00 → 09:00 Registration

09:00 → 09:10 INFN-LNS Introduction

Speaker: Aurora Tumino (Istituto Nazionale di Fisica Nucleare)

09:10 → 09:25 INFN Activity in the framework of Applied Physics

Speaker: Oscar Adriani (INFN-Firenze)

09:25 → 09:35 SIRR- Società Italiana per le Ricerche sulle Radiazioni: activities and purposes

Speaker: Giada Petringa (Istituto Nazionale di Fisica Nucleare)

09:35 → 09:50 INFN-4LS: Ongoing Activity and Development Projects

Speaker: Giacomo Cuttone (Istituto Nazionale di Fisica Nucleare)

09:50 → 10:20 Geant4 and Geant4-DNA: Monte Carlo Simulations Across Scales

Speaker: Luciano Pandola (Istituto Nazionale di Fisica Nucleare)

10:20 → 10:30 Irradiation of a preclinical model to study the molecular changes induced by non-ablative radiotherapy treatment in cardiac arrhythmias

Speaker: Francesco Cammarata (Istituto Nazionale di Fisica Nucleare)

10:30 → 11:00 Coffee Break

11:00 → 11:30 Geant4-DNA Chemistry Modelling: General Overview, current status and future developments

Speaker: Serena Fattori (INFN-LNS)

SIRR-2025_Serena-Fattori_vfinal.pptx

11:30 → 12:00 For a safer hadrontherapy: modelling and prediction of side effects

Speaker: Mario Pietro Carante (Istituto Nazionale di Fisica Nucleare)

sirr_2025.pptx

12:00 → 12:30 Human spaceflight around Earth and in deep space: monitoring, shielding, and modelling to protect future ESA missions in a harsh radiation environment

Speaker: Giovanni Santin (ESA / ESTEC)

GSantin SIRR 2025 ESA simulation space v1.05.pdf

12:30 → 13:00 Translational BNCT: Coupling Experimental Radiobiology with Model-Based Dosimetry

Speaker: Ian Postuma (Istituto Nazionale di Fisica Nucleare)

20251006_Postuma_SIRR.pdf

13:00 → 13:15 Shaping the Future: Strategic Roadmap for Ultrafast Radiation Biology with laser-driven radiations

Speaker: G.A.P. Cirrone (INFN-LNS)

Cirrone SIRR Catania Ottobre 2025.pptx

13:15 → 14:15 Lunch break

14:15 → 14:45 Radiation Biophysical modeling and understanding of Ultra-high dose rate response: present status and challenges

Speaker: Emanuele Scifoni (Istituto Nazionale di Fisica Nucleare)

SIRR_Modeling_Scifoni_OK1.pptx

14:45 → 15:00 Development of Geant4-DNA to simulate cosmic ray ionisation in the atmosphere

Speaker: Carlo Mancini Terracciano (Istituto Nazionale di Fisica Nucleare)

15:00 → 15:15 Deep learning emulation of Monte Carlo dose estimation

Speaker: Lorenzo Arsini

15:15 → 15:45 Down to the nanoscale: computational nanodosimetry and its link with radiobiology

Speaker: Anna Selva (Istituto Nazionale di Fisica Nucleare)

15:45 → 16:15 Advanced Simulation Tools for Medical Imaging and Radiation Therapy at the University and INFN Naples

Speaker: Dr Laura Antonia Cerbone

16:15 → 16:45 Coffee Break

16:45 → 17:00 Zebrafish (Danio rerio): a small preclinical model with great potential for radiobiological studies. From From basic analyses to future applications

Speaker: Gaia Pucci (Istituto Nazionale di Fisica Nucleare)

17:00 → 17:15 Dosimetric Evaluation of Very High Energy Electrons Generated by Plasma Discharge Capillaries

Speaker: Dr Sahar Arjmand (INFN-LNS)

17:15 → 17:30 Reverse Beam Engineering with Neural Surrogates: From LWFA Optimization to Geant4 Integration

Speaker: Alberto Sciuto (Istituto Nazionale di Fisica Nucleare)

17:30 → 17:45 Microtrack: A new example for ion track-structure Monte Carlo calculations in microdosimetry

Speaker: Miguel Galocha-Oliva (Universidad de Sevilla)

17:45 → 18:00 Computational modelling of cell fate following proton irradiation

Speaker: Agnieszka Jugowicz (University of Manchester)

18:00 → 18:15 111Ag-Mediated Intercellular Radiation for Target Breast Cancer Therapy

Speaker: Cristiana Alberghina (Istituto Nazionale di Fisica Nucleare)

SIRR2025_ppt Cristiana Alberghina_October 6th.pptx

18:15 → 18:30 Evaluation of boron-conjugated SRC inhibitor combined with proton irradiation in U87-MG and U-87 MG IDH1R132H cell lines

Speaker: Filippo Torrisi (University of Catania)

18:30 → 18:45 Optimization of the stack detector array - PRAGUE based on the Fermi-Eyges theory

Speaker: Alma Kurmanova (Istituto Nazionale di Fisica Nucleare)

18:45 → 19:00 Microdosimetric spectra evaluation for proton Minibeam Radiotherapy through Monte Carlo Geant4 simulations

Speaker: Dr Elena Corvaia