Nanotechnology innovations are the latest scientific/technological breakthroughs unveiled to the public within the last decade. Scientific advances, such as the Human Genome Project, CERN’s Large Hadron Collider, Cloning and the Hubble Space Telescope, to mention only a few, have changed the way we look at our world. These breakthroughs pose new and complex challenges for science communicators. How can we explain such diverse and intricate subjects in 60 seconds?–topics which require such a wide scientific base; and where often their title and the PR around them are much more attractive and appealing than the complicated explanation of their content.