16–20 Jun 2025
THotel, Cagliari, Sardinia, Italy
Europe/Rome timezone

One Shot Simulation-based Inference

18 Jun 2025, 16:33
3m
THotel, Cagliari, Sardinia, Italy

THotel, Cagliari, Sardinia, Italy

Via dei Giudicati, 66, 09131 Cagliari (CA), Italy
Poster + Flashtalk Inference & Uncertainty Parallel sessions - Inference & Uncertainty

Speaker

Ms Huifang Lyu (University of Amsterdam)

Description

Simulation-based inference (SBI) has seen remarkable development in recent years and has found widespread application across a range of physical sciences. A defining characteristic of SBI is its ability to perform likelihood-free inference, relying on simulators rather than explicit likelihood functions. Several representative methods have emerged within this framework, such as Approximate Bayesian Computation (ABC), Neural Posterior Estimation (NPE), and Neural Ratio Estimation (NRE). In this work, we present a variant of the SNPE family—One Shot Simulation-based Inference—which leverages Normalizing Flows to directly approximate the true posterior distribution with a trainable neural network. In parallel, we introduce a second network that learns an adaptive proposal distribution, which generates increasingly informative samples during training. This design eliminates the need for multiple inference rounds, significantly accelerates convergence, and reduces the overall computational cost. To demonstrate the effectiveness of this approach, we will show the application results of several model cases.

AI keywords simulation-based inference, normalizing-sequential flow, probability density estimate

Primary author

Ms Huifang Lyu (University of Amsterdam)

Co-authors

Prof. Christoph Weniger (University of Amsterdam) Dr James Alvey (University of Cambridge) Dr Mauro Pieroni (CERN) Dr Noemi Anau Montel (Max Planck Institute for Astrophysics)

Presentation materials

There are no materials yet.