17–23 Sept 2023
Hotel Hermitage, La Biodola Bay, Isola d'Elba, Italy
Europe/Rome timezone

Verification Simulation Studies for FLASH therapy Ultra-High-Dose Rate (UHDR) Beams

18 Sept 2023, 17:45
20m
Aula Elena (Hotel Hermitage)

Aula Elena

Hotel Hermitage

Oral contribution WG5: Applications WG5: Applications

Speaker

Prof. Evangelos Gazis (2) Institute of Accelerating Systems & Applications, 1) National technical University of Athens)

Description

The main results of the electron pulse and ultra-high-dose-rate (UHDR) parameter verification simulation studies are reported for the FLASH mode radiobiological treatment. There were reproduced the percentage depth dose (PDD) at energies: 5, 7, 15, 25, 50 and 100 MeV, to Poly-methyl-methacrylate (PMMA) and to water fantom vs the penetration depth. Additionally, the PDD transverse profile was simulated for the above energies and with various size applicators, delivering the beam to the fantom. Pencil mode beam size has been achieved with the optimum applicator geometry.
Simulations were, also, performed for various materials, PMMA, Al, Cu and Stainless Steel of the applicators, leading to the best material for the FLASH therapy. Beam distribution plots are presented vs the beam energy, the fantom material and applicator geometry.
The results show that the system can provide UHDR irradiation satisfying the FLASH requirements with very good performance in terms of the beam profile flatness for any size of the fields, depending, mainly, on the linear accelerator beam stability.

Primary author

Prof. Evangelos Gazis (2) Institute of Accelerating Systems & Applications, 1) National technical University of Athens)

Co-authors

Ms Melina Moniaki (1) National technical University of Athens) Dr Nick Gazis (European Spallation Source)

Presentation materials