May 17 – 20, 2015
La Biodola, Isola d'Elba
Europe/Rome timezone

Small Animal PET Based on 16x16 TSV-MPPCs and Monolithic Crystals

May 19, 2015, 9:30 AM
Room Maria Luisa

Room Maria Luisa

<a target="_blank" href=>Hotel Hermitage</a> </br>e-mail: <a href="">
Talk 2 - Advances in MR-PET instrumentation: systems Session 5 - Preclinical MR-PET and MR-SPECT: systems and applications


Antonio Gonzalez (Institute for Instrumentation in Molecular Imaging, i3M-CSIC)


In this work we present the design of a small animal PET based on 8 high-density arrays of MPPCs and monolithic scintillators. The MPPCs arrays are composed of 16x16 TSV-type (3x3 mm2) elements covering a rough active area of 5x5 cm2. A single LYSO block with a thickness of 10mm has been mounted on each detector. Black paint has been applied to the entrance and lateral faces of the crystal to preserve the scintillation light distribution. The axial and transaxial FOVs of one ring are 48 mm and 80 mm, respectively. Each MPPC array has been directly attached to a resistive readout circuit that provides outputs for each row and column of the array. These 32 signals are read with flexible boards 30 cm apart from the PET detector without any additional connectors in between. The PET-system is intended for in-line acquisition in front of MR-scanners and as PET-insert inside the sensitive MRI volume. For this purpose, it is necessary to avoid magnetic sensible materials, such as nickel, and to prevent eddy currents in metallic structures induced by the MRI gradients. All detectors are air cooled and kept at temperatures of approximately 20ºC with a variation below 0.05ºC. The intrinsic resolution is 2.2mm at the crystal center (averaged over all 2.6 mm) when Center of Gravity methods are used to resolve the impact position. This value is about a factor 1.5 better than results obtained with the H8500 PSPMT (64 PADs) and similar scintillators. With an improved collimator with holes with only 0.8mm diameter and a length of 70mm, an intrinsic detector resolution of 1.1mm was reached. The energy resolutions of ROIs of 1x1cm2 showed FWHM values in the range of (14±2)%.

Primary author

Antonio Gonzalez (Institute for Instrumentation in Molecular Imaging, i3M-CSIC)


Dr Albert Aguilar Talens (Institute for Instrumentation in Molecular Imaging, i3M-CSIC) Mr Carlos Correcher Salvador (Oncovision) Mr Cesar Molinos Solsona (Oncovision) Dr Jose Maria Benlloch (Institute for Instrumentation in Molecular Imaing, i3M-CSIC) Mr Konrad Lankes (Bruker BioSpin) Mr Liczandro Hernandez Hernandez (Institute for Instrumentation in Molecular Imaging, i3M-CSIC) Mr Luis Fernando Vidal San Sebastian (Institute for Instrumentation in Molecular Imaging, i3M-CSIC) Mr Pablo Conde (Institute for Instrumentation in Molecular Imaging (I3M)) Dr Sven Junge (Bruker BioSpin)

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