Conveners
Session 5 - Preclinical MR-PET and MR-SPECT: systems and applications
- Christer Hallding (Karolinska Institutet)
Patrick Hallen
(Department of Physics of Molecular Imaging Systems, RWTH Aachen University)
5/19/15, 8:30 AM
5 - Preclinical MR-PET
Talk
In this work we present detailed characterizations of our preclinical high resolution PET/MR insert based on the Hyperion-IID platform. The PET/MR insert consists of a ring of 10 singles detection modules, each comprising 2x3 scintillation detector stacks. Each detector stack features a 30x30 pixelated LYSO crystal array with a heigh of 12 mm and a pitch of 1 mm, coupled via a slit 2 mm light...
Andrew Goertzen
(University of Manitoba)
5/19/15, 8:50 AM
5 - Preclinical MR-PET
Talk
We have recently completed construction of a high resolution small animal PET insert designed for operatation inside a Bruker 7T MRI. The PET insert is designed to achieve a 1 mm spatial resolution in the centre of its field of view (FOV) and fit within the 114 mm inner diameter of the Bruker BGA-12S gradient coil while accommodating the Bruker 35 mm volume RF coil (outer diameter 60 mm). The...
Werner Lustermann
(ETH Zurich)
5/19/15, 9:10 AM
2 - Advances in MR-PET instrumentation: systems
Talk
SAFIR (Small Animal Fast Insert for mRi) is an innovative, high rate, PET detector insert for MRI, to be used for quantitative dynamic pre-clinical imaging, with very high activities injected in the animals, up to 500 MBq. The PET detector will be designed to allow for ultra short acquisition periods (of the order of a few seconds) simultaneously with the MRI, permitting unprecedented temporal...
Antonio Gonzalez
(Institute for Instrumentation in Molecular Imaging, i3M-CSIC)
5/19/15, 9:30 AM
2 - Advances in MR-PET instrumentation: systems
Talk
In this work we present the design of a small animal PET based on 8 high-density arrays of MPPCs and monolithic scintillators. The MPPCs arrays are composed of 16x16 TSV-type (3x3 mm2) elements covering a rough active area of 5x5 cm2. A single LYSO block with a thickness of 10mm has been mounted on each detector. Black paint has been applied to the entrance and lateral faces of the crystal to...
Heinz H. Coenen
(Institute of Neuroscience and Medicine, INM-5 - Nuclear Chemistry, Forschungszentrum Jülich)
5/19/15, 9:50 AM
8 - Bimodal MR-PET tracers
Talk
The development of small molecule bimodal PET/MR tracers is mainly hampered by the lack of dedicated preparation methods. Authentic radiolabelling of MR contrast agents ensures easy access to such probes: a ligand, chelating a paramagnetic metal ion (e.g. Mn2+) and the corresponding PET isotope (e.g. 52gMn), leads to a “cocktail mixture” where both imaging reporters exhibit the same...
Guen Bae Ko
(Seoul National University)
5/19/15, 10:10 AM
5 - Preclinical MR-PET
Talk
Lymph node (LN) imaging has clinical significance because the invasion status of the LN is crucial information for disease stratification, staging, and management. Compared with conventional method, simultaneous PET/MRI using the multi-modal imaging marker can offer synergistic advantages. Here, we present LN mapping using self-developed PET/MRI and novel bimodal biomarker.
The SiPM-based...
