26 May 2024 to 1 June 2024
La Biodola - Isola d'Elba (Italy)
Europe/Rome timezone

A 3D imaging system for dosimetry in FLASH radiotherapy

28 May 2024, 08:31
3h 59m
Sala Elena

Sala Elena

Poster T5 - Applications to Industrial and Societal Challenges Applications to Industrial and Societal Challenges - Poster session

Speaker

Eleonora Ravera (Università di Pisa / INFN)

Description

In recent years, the advent of Flash radiotherapy has called for a paradigm shift in dosimetry. The Flash effect demands an administration of an average dose rate higher than 40 Gy/s, as opposed to 1 Gy/min in conventional radiotherapy, introducing saturation challenges in standard dosimeters. Moreover, rapid optimization of beam settings and quality assurance protocols require detectors for online, accurate volumetric measurement of delivered dose distributions at high dose rates. Given the limitations of commonly used 3D dosimeters in terms of reusability and signal readout speed, there is a growing interest in plastic scintillators for their real-time capability, tissue equivalence and cost-effectiveness. Although some 3D dosimetric systems based on plastic scintillators have been developed for conventional radiotherapy, there is a lack of validation and optimization of techniques specific for Flash radiotherapy.
In this study, we present the first results of an imaging system made by an EJ200 (Eljen Technology) plastic scintillating block measuring 10x10x10 cm$^3$, irradiated with a high dose rate beam of 9 MeV electrons at the Pisa Center for Flash Radiotherapy (CPFR). Images were captured at various doses per pulse within the flash regime using a scientific CCD camera (Hamamatsu ORCAII-BT-512G) coupled to an objective (Schneider Optics Xenon). During irradiation, the camera and the objective were positioned at a distance of 10 cm orthogonally to the block, which was aligned along the beam axis. This imaging system will enable the validation of a dose delivery reconstruction algorithm based on acquiring multi-projections of 2D light distributions with a single CCD camera and a set of mirrors.

Role of Submitter I am the presenter

Primary author

Eleonora Ravera (Università di Pisa / INFN)

Co-authors

Rebecca Anzalone (Università di Pisa) Andrea Cavalieri (Università di Pisa) Esther Ciarrocchi (Istituto Nazionale di Fisica Nucleare) Damiano Del Sarto (Università di Pisa) Fabio Di Martino (U.O. Fisica Sanitaria, AOUP) MATTEO MORROCCHI (Istituto Nazionale di Fisica Nucleare) Maria Giuseppina Bisogni (Istituto Nazionale di Fisica Nucleare)

Presentation materials