Estimating skeletal muscle metabolism from 31P MRSI at 7 Tesla using a dual-tuned volume coil preliminary in-vivo results

20 May 2024, 18:55
5m
La Biodola, Isola d'Elba

La Biodola, Isola d'Elba

Hotel Hermitage
Poster Next-gen MR Poster Session

Speaker

Laura Biagi (IRCCS Stella Maris)

Description

Phosphorus Magnetic Resonance Spectroscopy (31P MRS) is a non-invasive imaging technique that estimates concentrations of high-energy phosphates, offering insights into cell metabolism and neuromuscular disorders. Its clinical adoption is hindered by the need for specialized coils, but using a volume coil dual-tuned to 1H and 31P for 3D Magnetic Resonance Spectroscopy Imaging (3D-MRSI) can overcome this difficulty. Our approach allows for fast acquisition with improved spectral resolution at Ultra-High Field (7T). This approach can potentially enhance 31P metabolic imaging in clinical settings.

Field Software and quantification

Primary authors

Bianca Buchignani (IRCCS Stella Maris) Giacomo Aringhieri (IMAGO7 Foundation) Laura Biagi (IRCCS Stella Maris) Michela Tosetti (IRCCS Stella Maris and IMAGO7 Research Foundation) Paolo Cecchi (IMAGO7 Foundation) Pierfrancesco Ambrosi (IRCCS Stella Maris) Roberta Battini (Università di Pisa) Rolf F. Schulte (GE HealthCare)

Presentation materials