4th Conference on PET/MR and SPECT/MR

Session

Session 4 - Advances in MR-PET and MR-SPECT Software and Quantification

18 May 2015, 18:00

La Biodola, Isola d'Elba

Conveners

Session 4 - Advances in MR-PET and MR-SPECT Software and Quantification

• Dimitris Visvikis (INSERM)

22. Automatic Derivation of an MR-PET Image-Based Input Function for Quantification of 18F-FET

Nuno André da Silva (Institute of Neuroscience and Medicine - 4, Forschungszentrum Juelich)

18/05/2015, 18:00

3 - Advances in MR-PET and MR-SPECT software and quantification

Talk

Aim: Fully quantitative PET data requires an input function (IF) for kinetic modelling that is often acquired via arterial blood sampling. Here, an automatic method to obtain an image-derived input function (IDIF) using MR-PET data is presented and several partial volume correction methods (PVC) are evaluated. Material and methods: Data from three tumour patients were acquired in a 3T...

23. Cross Calibration of the Siemens mMR: Easily Acquired Accurate PET Phantom Measurements, Long Term Stability and Reproducibility

Sune H. Keller (Rigshospitalet, University of Copenhagen, Denmark)

18/05/2015, 18:20

3 - Advances in MR-PET and MR-SPECT software and quantification

Talk

We present a quick and easy method to perform quantitatively accurate PET scans of typical water-filled PET plastic shell phantoms on the Siemens mMR PET/MR scanner. We perform regular cross calibrations (Xcals) of our PET scanners, including the Siemens mMR PET/MR, with a Siemens mCT water phantom. We evaluate the mMR cross calibration stability over a 3-year period. Recently, the mMR...

24. Pseudo-CT Generation in Brain MR-PET Attenuation Correction: Comparison of Several Multi-Atlas Methods

Inés Mérida (1 - Université de Lyon 1, INSERM, CNRS, Lyon Neuroscience Research Center, France, 2 - LILI-EQUIPEX – Lyon Integrated Life Imaging: hybrid MR-PET, 3 - Siemens Healthcare France SAS, Saint-Denis, France)

18/05/2015, 18:40

3 - Advances in MR-PET and MR-SPECT software and quantification

Talk

Simultaneous MR-PET imaging opens new perspectives for understanding many aspects of brain function. However, accurate brain attenuation correction (AC) is required for absolute PET quantification. Radiodensity maps for AC are not readily available in PET-MR. Various strategies have been proposed to generate substitute attenuation maps. Recently, it has been shown that multiatlas techniques...

26. Simultaneous Reconstruction of Attenuation and Activity for non–TOF PET/MR Using MR Prior Information

Thorsten Heußer (German Cancer Research Center (DKFZ), Heidelberg, Germany)

18/05/2015, 19:00

3 - Advances in MR-PET and MR-SPECT software and quantification

Talk

Accurate quantification of the activity distribution in positron emission tomography (PET) mandates attenuation correction (AC). Unlike in PET/CT, AC in PET/MR is, however, challenging, since direct information about the attenuation properties of the patient tissue distribution is not available directly. Standard MR-based AC (MRAC) does not account for the presence of bone and, thus, yields an...

81. A Multi-Modal Fusion Scheme for the Enhancement of PET/MR Viewing

Marco Aiello (IRCCS SDN, Napoli, IT)

18/05/2015, 19:20

3 - Advances in MR-PET and MR-SPECT software and quantification

Talk

PET/MR imaging offers the possibility to achieve in one-shot both functional information provided by PET imaging and morpho-functional information with excellent soft tissue contrast provided by MRI. As a result of a typical PET/MR acquisition, each voxel carries a large amount of multivariate information that can be combined into a single image for a synthetic multi-parametric viewing (image...