May 17 – 20, 2015
La Biodola, Isola d'Elba
Europe/Rome timezone

Development of Compact DOI-Measurable PET Detectors for Simultaneous PET/MR Imaging

May 20, 2015, 8:30 AM
Room Maria Luisa

Room Maria Luisa

Talk 1 - Advances in MR-PET instrumentation: detectors Session 10 - Clinical MR-PET


Yiping Shao (University of Texas MD Anderson Cancer Center)


It is critically needed yet challenging to develop compact PET detectors with high sensitivity and uniform, high imaging resolution for improving the performance of simultaneous PET/MR imaging, particularly for an integrated/inserted small-bore system. Using latest “edge-less” SiPM arrays for DOI measurement using the design of dual-ended-scintillator readout, we developed several compact PET detectors suited for PET/MR imaging. Each detector consists of one LYSO array with each end coupled to a SiPM array. Multiple detectors can be seamlessly tiled together along all sides to form a large detector panel. Detectors with 1.5x1.5 and 2.0x2.0 mm crystals at 20 or 30 mm lengths were studied. Readout of individual SiPM or capacitor-based signal multiplexing was used to transfer 3D interaction position-coded analog signals through flexible-print-circuit cables to dedicated ASIC front-end electronics to output digital timing pulses that encode interaction information. These digital pulses can be transferred to, through standard LVDS cables, and decoded by a FPGA-based data acquisition positioned outside the MRI scanner for coincidence event selection. Initial detector performance measurement shows excellent crystal identification even with 30 mm long crystals, ~18% and 2.8 ns energy and timing resolutions, and around 2-3 mm DOI resolution. A large size detector panel can be scaled up with these modular detectors and different PET systems can be flexibly configured with the scalable readout electronics and data acquisition, providing an important design advantage for different system and application requirements. It is expected that standard shielding of detectors, electronics and signal transfer lines can be applied for simultaneous PET/MR imaging applications, with desired DOI-measurement capability to enhance the PET performance and image quality.

Primary author

Yiping Shao (University of Texas MD Anderson Cancer Center)


Mr Kai Lou (Rice University) Dr Xishan Sun (University of Texas MD Anderson Cancer Center)

Presentation materials