EUROPEAN RADIATION RESEARCH 2012

Effect of surgical stress and immobility of the hormone Ghrelin and body weight and food consumption in adult male rats

17 Oct 2012, 16:20

1m

Poster Hall (Vietri sul Mare)

poster preferred Other Poster Session 2

Speaker

Mr mojtaba keshavarz (Msc Of Developmental Biology , Department Of Biology,Islamic azad university of jahrom , jahrom,, Fars, Iran.)

Description

Introduction: Ghrelin is a hormone that was discovered in 1999 by kojima where stomach cells that secrete this hormone increases growth hormone secretion and the amount of food consumed has a significant role stress can increase blood levels of Ghrelin is the purpose of this study surgical stress and immobility in periods 7 and 14 days on the secretion of Ghrelin and body weight and food is consumed. Methods: In this experimental study of 60 adult male rats were used in animals were randomly divided into 6 groups. The first group and second group served as controls were studied groups 3 and 4 were operated and then after 7 and 14 days of weighing to the blood sampling was performed, groups 5 and 6 also stress immobility, respectively. were for 7 and 14 days and then blood samples were taken and Ghrelin levels were measured in serum samples. Results: Ghrelin levels in serum had no significant effect on surgical stress. Stress immobility Serum Ghrelin levels were significantly increased. Effects stress Ghrelin serum levels greater than 14 groups on 7-day stress is immobility. Stress immobility for 14 days significantly decreased body weight than the control group. (Mean ± sem) food intake for both the significant increase in stress. Conclusion: Ghrelin increased serum level of immobility stress, weight loss and food intake is increased. Key words: Surgical stress, immobility stress, Ghrelin, male rat