Description
This session will be on display on Monday morning and Tuesday morning
Link to the contributions
In recent years, the advent of Flash radiotherapy has called for a paradigm shift in dosimetry. The Flash effect demands an administration of an average dose rate higher than 40 Gy/s, as opposed to 1 Gy/min in conventional radiotherapy, introducing saturation challenges in standard dosimeters. Moreover, rapid optimization of beam settings and quality assurance protocols require detectors for...
Recent studies shown and increased effectiveness of radiotherapy (RT) and particle therapy (PT) in treating tumors while minimizing damage to healthy tissue in presence of an ultra-high dose rates (~100 Gy/s). The phenomena, called Flash effect, requires the dose to be delivered concentrated in a short time (<500 ms). However, conventional detectors face challenges in monitoring charged beams...
The CHNet-MAXI (Muonic Atom X-ray and prompt gamma spectroscopy for Isotopic analysis for cultural heritage) is an INFN Cultural Heritage program funded by Scientific Commission V, aiming at selecting the best figures of merit in the isotopic analysis of lead by means of muonic atom emission. The experiment will be deployed at RIKEN-RAL facility ISIS-STFC (UK), providing a pulsed muon beams...
Particle therapy employs protons and heavy ions for treating deep-seated tumours, yet the biological impact of beam-induced tissue fragmentation remains a crucial concern. Despite the importance of target fragmentation effects, their assessment is challenging, and they are often overlooked in clinical practice. To enhance current clinical treatment plans, precise data on fragmentation cross...
In the past few years, Electronic Portal Imaging Device (EPID) have gained prominence for pre-treatment dose verification and real-time monitoring in radiotherapy. These detectors function by recording the X-ray fluence on a pixel-based surface to produce a two-dimensional digital image. Their rapid image capturing ability, high resolution, good linear dose response, and long-term stability...
Knowledge of the precise location of the Bragg Peak (BP) in proton therapy is crucial for optimizing its therapeutic effects and to minimize the damage to healthy tissues in cancer treatment [1]. In this work, we present test results and simulations of the light emitted by organic scintillators exposed to different proton energies and visualised by multiple cameras to reconstruct the BP....
In recent years, the introduction of accelerator-based BNCT facilities has led to a significant increase in interest from the medical and scientific communities.
Monitoring and characterization of neutron beams and intercomparison of different facilities are becoming mandatory.
This stimulates the development of dedicated dosimetry and spectrometry techniques. This work aims to present a...
This paper introduces a novel concept for a charge detector featuring high resolution and a wide dynamic range. The prototype of this detector was specifically designed and constructed to serve the ion beam monitoring requirements of the High-Energy cosmic-Radiation Detection (HERD) experiment during beam tests conducted at CERN SPS facilities.
The prototype incorporates a series of silicon...
Research and development on 3D integrated digital silicon photo-multipliers is motivated by the growing interest in high-energy physics, medical and telecommunication communities. The race in particle accelerators and noble liquid experiments to enable more precise vertex reconstruction implies the need to reduce the timing jitter of the whole electronic chain while increasing the detecting...
Time of flight positron emission tomography (TOF-PET) is a 3D medical imaging technique, used to measure biological activity down to a sensitivity of a picoMol. PET detectors typically consist of a scintillating crystal, photodetector and readout electronics. The time-of-light technique I allows one to inject a lower dose to the patients, to reduce computing time, and for better quality...
This work focuses on creating two neural networks to optimize the analysis of data from ring laser gyroscopes, as in the case of the GINGER experiment at Gran Sasso. The Gingerino prototype provides data for deriving Earth's rotation, polar motion, earthquake detection, and distinguishing rotational components of tides. However, offline analysis using the Hilbert transform takes about 10...
Space is an environment permeated by different forms of radiation, each with its own characteristics and effects. Studies in this scientific field offer a unique window into the universe, providing important information about the origin, composition, and evolution of the cosmos.
However, space radiation also poses significant challenges for space exploration. Radiation exposure in space has...
To ensure optimal patient safety with Proton Beam Therapy (PBT), several beam properties are measured as part of Quality Assurance (QA), with the proton range in water being a key parameter. Due to time restrictions in daily QA, comprehensive measurements are not made. Among many other technical challenges in realising FLASH PBT, current methods for range QA become unusable at the required...
The presented device is a compact gamma and fast neutron data acquisition system (DAQ) for passive and active NDA of SNM (Special Nuclear Materials). The DAQ weights just 8 kg, including batteries for more than 8 hours of continuous operation. It connects up to 4 organic detectors with Pulse Shape Discrimination (PSD) capabilities and runs PSD in real time on the radiation signals. It measures...
The Medipix3 is a hybrid pixel detector capable of individually counting protons with millisecond time resolution, even at clinical flux levels. With near-instant readout and count rate linearity, it proves to be suitable for dosimetry and beam characterization in proton therapy facilities. In this study, we present test results conducted at the Clatterbridge Cancer Centre (CCC) in the UK, a...
The negative capacitance (NC) feature exhibited by doped high-k dielectric HfO2 has emerged as a crucial technological advancement in CMOS nanoscale electronic devices. The revelation of ferroelectricity in HfO2 opens up new possibilities for manufacturability and scalability across various domains, and the design of low-power, sharply switching transistors. The resilience of ferroelectricity...
We present a design project for a muon tomography detector aiming to the
monitoring of glacier thickness: the glacier melting process is not completely understood and is considered a hot topic in view of the global warming.
Muon Tomography is a widely used technique, employed to perform imaging
of the inner structure of large objects, as volcanoes, container, and pyramids.
This technique...
In recent decades organic electronics has entered the mainstream of consumer electronics. Driven by innovations in scalability and low power applications, and low-cost fabrication methods. The potential for using organic semiconductor electronic devices as radiation detectors, and in particular for neutron detection is reported. We report results of laboratory tests using α particles as...
Background. FLASH Radiotherapy (RT) delivers an average dose-rate > 40 Gy/s in less than 200 ms with extremely high instantaneous dose-rates, and preclinical studies demonstrated a tumoricidal effect comparable to conventional RT with an increased sparing effect on healthy tissues (FLASH effect). Real-time monitoring of FLASH beams is challenging, but crucial for studying the delivery...
Muography is an imaging technique based on the detection of muons produced naturally in the atmosphere with applications in Volcanology, Archaeology, Civil Engineering, Homeland Security etc. Various types of background impact absorption tomography measurements at high zenithal detection angles. Trackers combined with Cherenkov detectors have been proposed as means for better background...
Neutron detectors are crucial for various research fields, including nuclear, particle, and astroparticle physics, as well as hadrontherapy and radiation protection. Not ionizing directly, neutrons are detected via nuclear interactions producing charged particles or electromagnetic radiation. As a result, the detection efficiency depends on the probability of neutron interaction in the...
The Global Cancer Observatory reports that in 2020 the European population had a 28.2% risk of developing cancer before the age of 75 years, with a 11.7% mortality risk. Such mortality rate can be reduced through early detection of tumours by means of imaging techniques. Among them, nuclear imaging scans play a pivotal role for noninvasive diagnosis. This contribution is focused on Single...
Timepix4 is the latest generation application-specific integrated circuit (ASIC) of the Timepix family, developed by the Medipix4 Collaboration, and mainly targeted for single particle detection in hybrid pixel detectors.
It is built in $65\;nm$ CMOS technology, and it allows to achieve excellent resolutions, thanks to a pixel pitch of $55\;\mu m$, a Time-to-Digital Converter bin size of...
