The reSPECT project for a flexible and fast total body nuclear imaging diagnoses with high-Z organic scintillators

22 May 2024, 16:40
5m
La Biodola, Isola d'Elba

La Biodola, Isola d'Elba

Hotel Hermitage
Poster Total body imaging Poster Session

Speaker

Michela Marafini (CREF Centro Ricerche Enrico Fermi, Rome, Italy)

Description

In this contribution we present a new total body SPECT gamma detector concept that relies on a tungsten metal frame, that serves both as a collimator and as a container for the scintillator segments, organized in a grid geometry with holes of few millimeter (diameter). The active material is organic scintillators enriched with high-Z elements allowing to profit of the extremely fast scintillation process and a reduction in costs. The enriched scintillator produced for this reSPECT project have been loaded with Bismuth in concentration from 2 up to 10%. The results are promising in terms of light output and photon-interaction probability via photoelectric effect. A readout system that can properly integrate the short signals and handle high event rates is needed; we therefore considered a custom design tuned for fast scintillation events with an independent channel for each scintillator segment allowing for possible applications of SPECT in advanced theragnostic. Multiple FPGA-based modules will combine the readout channels and pre-process the data in real-time.
Images from patients of Policlinico Umberto I Hospital have been exploited as starting point for a Montecarlo based reconstruction study with the aim of optimizing the detector geometry and of evaluate the achievable performances. In this contribution, the expected performances of a total body system will be presented together with the results obtained with the first prototypes.

Field Systems and applications

Primary authors

Alberto Burattini (Istituto Nazionale di Fisica Nucleare) Alessio Sarti (La Sapienza - INFN Roma 1) Angelica De Gregorio (Istituto Nazionale di Fisica Nucleare) Angelo Schiavi (SBAI Department, Sapienza University of Rome) Annalisa Muscato (Sapienza University of Rome, Post-graduate School in Medical Physics, Rome, Italy) Daniele Rocco Enrico Manuzzato (FBK) Flaminia Quattrini (Istituto Nazionale di Fisica Nucleare) Gaia Franciosini (Istituto Nazionale di Fisica Nucleare) Giacomo Traini (Istituto Nazionale di Fisica Nucleare) Giuseppe De Vincentis (Department of Radiological Sciences, Oncology and Anatomo-Pathology, University of Rome, Rome, Italy) Leonardo Gasparini (FBK) Leonardo Mattiello (Sapienza University of Rome, Department SBAI, Rome, Italy) Marco Garbini Marco Magi (Istituto Nazionale di Fisica Nucleare) Marco Toppi (Istituto Nazionale di Fisica Nucleare) Michela Marafini (CREF Centro Ricerche Enrico Fermi, Rome, Italy) Nils Krah (University Lyon, CNRS, CREATIS, Lyon, France) Roberto Passerone (University of Trento, Department of Information Engineering and Computer Science, Trento, Italy) Viviana Frantellizzi (Department of Radiological Sciences, Oncology and Anatomo-Pathology, University of Rome, Rome, Italy) marta David (Sapienza University of Rome, Department SBAI, Rome, Italy) vincenzo patera (Universita' di Roma "La Sapienza" & INFN)

Presentation materials