Biofisica

Innovative Chemistry and Physical Energy to Optimize Stem Cell Reprogramming and Expression of Pluripotentiality

by Prof. Carlo Ventura (Università di Bologna)

Europe/Rome
Sala Lauree (Dipartimento di Fisica - Ed. G. Marconi)

Sala Lauree

Dipartimento di Fisica - Ed. G. Marconi

Description
Stem cells may hold promise for the rescue of severely damaged tissues. Many efforts are dedicated to affect cell growth and differentiation, and maximize stem cell pluripotentiality. We present evidence that cardiogenesis could be efficaciously turned on in mouse embryonic stem (ES) cells by extremely low frequency magnetic fields (ELF-MF). We also exposed mouse ES cells to a Radio Electric Asymmetric Conveyer (REAC), an innovative device delivering Wi-Fi RF of 2.4 GHz. REAC exposure enhanced the expression of cardiac, skeletal and neuronal lin! eage-restricted marker proteins. The number of spontaneously beating ES-derived myocardial cells was also increased.