Liquid Crystal-Based Biosensors for Sensitive Detection of Biological Analytes at Aqueous Interfaces

by Susanta Sinha Roy (Department of Physics, Shiv Nadar University, Delhi (India))

Friday 21 Mar 2025, 16:00 → 17:00 Europe/Rome

Aula Conversi (Dip. di Fisica - Edificio G. Marconi)

Liquid crystal (LC)-based optical biosensors offer a novel approach for detecting biological
analytes. Two innovative biosensor designs were developed in our laboratory: one for detecting norfloxacin with a sensitivity of 5 nM, and another for detecting bacteremia via 16S rRNA with a limit of detection of 0.02 nM. These [1-2] biosensors demonstrated high sensitivity and label-free detection capabilities in complex matrices and human blood samples. They have significant potential for environmental and clinical applications, including public health and safety.

[1] Das, S. et al., 2024. Analyst, 149, pp. 3828-3838.
[2] Das, S. et al., 2025. Journal of Colloid and Interface Science, 683, pp.79-89.