Feb 15 – 19, 2026
Grand Hotel Mediterraneo
Europe/Rome timezone
12th International Conference on Isotopes - 12ICI

DEVELOPMENT OF AN AUTOMATED ELECTROPLATING SYSTEM FOR SOLID TARGET PREPARATION IN ALPHA EMITTER PRODUCTION

Feb 16, 2026, 2:06 PM
2m
Americas Room (Grand Hotel Mediterraneo)

Americas Room

Grand Hotel Mediterraneo

Poster 1. Isotopes Production and Devices Poster Session 1

Speaker

Mario Malinconico (COMECER S.p.A. - R&D Department)

Summary

The growing interest in Targeted Alpha Therapy (TAT) has intensified worldwide research on several alpha-emitting radionuclides, including 225Ac, 213Bi, 212Pb/228Th, 211At. These isotopes offer exceptional therapeutic potential due to their short-range, high-linear-energy-transfer radiation capable of selectively eradicating tumor cells while minimizing damage to surrounding healthy tissue. Among them, 225Ac is currently one of the most promising candidates; however, its large-scale, GMP-compliant production remains challenging. While cyclotron-based routes such as 226Ra(p,2n)225Ac have been demonstrated, automated and contamination-safe systems for target preparation are still lacking. This study have confirmed the feasibility of electroplating alkaline-earth and actinide elements, paving the way for solid target development for alpha emitter generation.

Are you interested/eligible for the Young Session? No, I am not eligible

Author

Mario Malinconico (COMECER S.p.A. - R&D Department)

Co-authors

Alessandro Brunetti (COMECER S.p.A. - R&D Department) Marco Testa (COMECER S.p.A. - R&D Department)

Presentation materials

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