Feb 15 – 19, 2026
Grand Hotel Mediterraneo
Europe/Rome timezone
12th International Conference on Isotopes - 12ICI

OPERATIONALIZING A NUCLEAR DIGITAL TWIN FOR MEDICAL ISOTOPE IRRADIATION PLANNING TO MEET CLINICAL DEMAND

Feb 17, 2026, 4:59 PM
15m
Plenaria: Africa Room (Grand Hotel Mediterraneo)

Plenaria: Africa Room

Grand Hotel Mediterraneo

Oral presentation 1. Isotopes Production and Devices 1. Isotopes Production and Devices - Tue_S3_A

Speaker

Soha Aslam

Summary

The United States is a global leader in nuclear technology, yet access to key medical isotopes remain fragile due to limited global production capacity, reliance on foreign reactors, and short isotopes half-lives. To address this, we have developed the first ML-driven Medical Isotope Planning Digital Twin (MIP-DT) to optimize nuclear reactor-based production of medical isotopes. Our goal is to increase isotope yield and throughput directly, supporting access to lifesaving diagnostics and therapies for cancer, cardiovascular, and neurological diseases. This work evaluates a series of irradiation scenarios for Sm-152 at UT Austin’s TRIGA Mk-II reactor. The objective was to ensure safe reactor operations while producing the target activity of Sm-153 required for a 150 mCi patent dose.

Are you interested/eligible for the Young Session? Yes, I am eligible and interested in participating

Author

Soha Aslam

Co-authors

Dr Benjamin Collins (University of Texas at Austin) Dr Kevin Clarno (University of Texas at Austin) Dr Nicholas Luciano (University of Texas at Austin) Dr William Charlton (University of Texas at Austin)

Presentation materials

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