Feb 15 – 19, 2026
Grand Hotel Mediterraneo
Europe/Rome timezone
12th International Conference on Isotopes - 12ICI

TECHNETIUM-94m PRODUCTION BY CYCLOTRON IRRADIATION OF PHOSPHOMOLYBDIC ACID USING AN AUTOMATED LIQUID TARGET SYSTEM

Feb 17, 2026, 2:44 PM
15m
Plenaria: Africa Room (Grand Hotel Mediterraneo)

Plenaria: Africa Room

Grand Hotel Mediterraneo

Oral presentation 1. Isotopes Production and Devices 1. Isotopes Production and Devices - Tue_S2_A

Speaker

Chloe Green (McMaster University)

Summary

The limited spatial resolution of single photon emission computed tomography (SPECT) imaging has prompted growing interest in developing positron emission tomography (PET) radioisotopes. Technetium-94m is viewed as a promising PET candidate, and initial work showed that phosphomolybdic acid (PMA) has the ability to be an effective target material for its production. Using our in-house designed liquid target automation (LTA) system, our group has demonstrated consistent technetium-94m production with experimental results comparable to our previously reported data. Additionally, our group is employing Monte Carlo modelling of the PMA irradiation set up to investigate how thermal and physical effects in a liquid target may affect the activity yield. Future work includes adjusting the simulations to account for liquid dynamics, experimentally determining maximum irradiation parameters, and evaluating technetium-94m tracer labeling for preclinical use.

Are you interested/eligible for the Young Session? Yes, I am eligible and interested in participating

Author

Chloe Green (McMaster University)

Co-authors

Jordan Cale (McMaster University) Dr Karin Nielsen (McMaster University) Leeon Fernandez (McMaster University) Dr Michael Farquharson (McMaster University) Ross Harper (McMaster University) Dr Stephen Archibald (King's College London)

Presentation materials

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