Speaker
Summary
The limited spatial resolution of single photon emission computed tomography (SPECT) imaging has prompted growing interest in developing positron emission tomography (PET) radioisotopes. Technetium-94m is viewed as a promising PET candidate, and initial work showed that phosphomolybdic acid (PMA) has the ability to be an effective target material for its production. Using our in-house designed liquid target automation (LTA) system, our group has demonstrated consistent technetium-94m production with experimental results comparable to our previously reported data. Additionally, our group is employing Monte Carlo modelling of the PMA irradiation set up to investigate how thermal and physical effects in a liquid target may affect the activity yield. Future work includes adjusting the simulations to account for liquid dynamics, experimentally determining maximum irradiation parameters, and evaluating technetium-94m tracer labeling for preclinical use.
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