Feb 15 – 19, 2026
Grand Hotel Mediterraneo
Europe/Rome timezone
12th International Conference on Isotopes - 12ICI

OPTIMIZING SOLID-TARGET PRODUCTION OF NON-CONVENTIONAL THERANOSTIC RADIONUCLIDES AT THE BERN MEDICAL CYCLOTRON

Feb 17, 2026, 11:40 AM
20m
Plenaria: Africa Room (Grand Hotel Mediterraneo)

Plenaria: Africa Room

Grand Hotel Mediterraneo

Oral presentation 1. Isotopes Production and Devices 1. Isotopes Production and Devices - Tue_S1_A

Speaker

Saverio Braccini (University of Bern)

Summary

This work reports on solid-target developments for the production of non-conventional theranostic radionuclides at the Bern medical cyclotron laboratory. The facility combines an IBA Cyclone 18/18 HC cyclotron, a Nirta Solid Target Station, and a dedicated Beam Transfer Line, enabling parallel GMP radiopharmaceutical production and research. A novel aluminium irradiation capsule was developed for safe handling of enriched materials, while accelerator upgrades and dedicated beam-monitoring tools ensured precise beam extraction, alignment, and control. Methodologies were established to measure beam energy and nuclear cross sections with high accuracy, enabling optimised yield and radionuclidic purity. Studies were performed for several medically relevant radionuclides, including scandium, copper, gallium, technetium, terbium, erbium, and thulium isotopes, leading to improved nuclear data. The results demonstrate that compact medical cyclotrons, equipped with optimised solid-target technology, can play a central role in the future production and dissemination of novel theranostic radionuclides.

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Authors

Alexander Gottstein (Albert Einstein Center for Fundamental Physics (AEC), Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse 5, 3012 Bern, Switzerland) Eva Kasanda (Albert Einstein Center for Fundamental Physics (AEC), Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse 5, 3012 Bern, Switzerland) Gaia Dellepiane (Albert Einstein Center for Fundamental Physics, Laboratory of High Energy Physics, University of Bern, Switzerland) Isidre Mateu (Albert Einstein Center for Fundamental Physics (AEC), Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse 5, 3012 Bern, Switzerland) Lars Eggimann (Albert Einstein Center for Fundamental Physics (AEC), Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse 5, 3012 Bern, Switzerland) Paola Scampoli (Albert Einstein Center for Fundamental Physics (AEC), Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse 5, 3012 Bern, Switzerland) Pierluigi Casolaro (Department of Physics Ettore Pancini, University of Napoli Federico II, 80126 Napoli, Italy) Saverio Braccini (University of Bern)

Presentation materials