Speaker
Summary
This work reports on solid-target developments for the production of non-conventional theranostic radionuclides at the Bern medical cyclotron laboratory. The facility combines an IBA Cyclone 18/18 HC cyclotron, a Nirta Solid Target Station, and a dedicated Beam Transfer Line, enabling parallel GMP radiopharmaceutical production and research. A novel aluminium irradiation capsule was developed for safe handling of enriched materials, while accelerator upgrades and dedicated beam-monitoring tools ensured precise beam extraction, alignment, and control. Methodologies were established to measure beam energy and nuclear cross sections with high accuracy, enabling optimised yield and radionuclidic purity. Studies were performed for several medically relevant radionuclides, including scandium, copper, gallium, technetium, terbium, erbium, and thulium isotopes, leading to improved nuclear data. The results demonstrate that compact medical cyclotrons, equipped with optimised solid-target technology, can play a central role in the future production and dissemination of novel theranostic radionuclides.
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