Speaker
Summary
This study investigates the production of 133La and 135La from barium targets for theranostic applications via the nuclear reactions 134Ba(p,2n)133La and 135Ba(p,n)135La, respectively. Cross sections of all reactions producing lanthanum radioisotopes up to 18 MeV were measured using natural Ba, 134Ba-, and 135Ba-enriched targets to disentangle contributions from different reactions. Production routes were evaluated for both an 18 MeV medical cyclotron and the future 15 MeV high-current CHeFS linac facility. Production tests at the Bern medical cyclotron confirmed the feasibility of solid target irradiation, while the high currents anticipated at CHeFS could enable unprecedented yields. Some of the investigated reactions were, as far as we know, measured for the first time, providing novel data to support the development of reliable production strategies for lanthanum theranostic radionuclides.
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