Feb 15 – 19, 2026
Grand Hotel Mediterraneo
Europe/Rome timezone
12th International Conference on Isotopes - 12ICI

OPTIMIZING SCANDIUM-44 PRODUCTION AND RADIOLABELING FOR POTENTIAL CLINICAL APPLICATION IN NUCLEAR MEDICINE

Feb 16, 2026, 5:46 PM
15m
Plenaria: Europa Room (Grand Hotel Mediterraneo)

Plenaria: Europa Room

Grand Hotel Mediterraneo

Oral presentation 2. Isotope Applications 2. Isotope Applications - Mon_S3_C - Young Session

Speaker

Marie Théry (PSI Center for Life Sciences, Villigen-PSI, Switzerland)

Summary

44Sc is a promising candidate for PET imaging and can be produced at medical cyclotrons via the 44Ca(p,n)44Sc reaction using highly enriched 44Ca targets. This study focuses on optimizing the production and purification of 44Sc to improve chemical purity and apparent molar activity, enhancing its potential for both preclinical and clinical applications. New separation methods using DGA (TrisKem International) and DOODA (Eichrom Technologies) resins were evaluated for their ability to efficiently separate scandium from macro quantities of calcium using hydrochloric acid, nitric acid and ammonium acetate as eluents. Based on these results, DGA and DOODA resins show comparable performance and have shown promise towards improved reproducibility.

Are you interested/eligible for the Young Session? Yes, I am eligible and interested in participating

Author

Marie Théry (PSI Center for Life Sciences, Villigen-PSI, Switzerland)

Co-authors

Ms Ana Katrina Mapanao (PSI Center for Life Sciences, Villigen-PSI, Switzerland) Anzhelika Moiseeva (PSI) Ms Cristina Müller (PSI Center for Life Sciences, Villigen-PSI, Switzerland) Nick van der Meulen Pascal V. Grundler (PSI) Roger Schibli (Paul Scherrer Institute)

Presentation materials

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