John Cesar
(The University of Texas at Austin)
In-beam PET imaging could herald a new era of more accurate and efficient dose in proton beam treatments with the potential to greatly improve patient outcomes. Such advancements would be even more important in the not-yet-understood but highly promising ultra-high dose and dose rate (FLASH) modality. In this talk we present our efforts to demonstrate the benefits of in-beam PET imaging. Our Time-of-Flight PET for Proton Therapy (TPPT) project focuses on a novel PET scanner designed and built to provide feedback during proton therapy treatments (proton range verification). We discuss results of our in-beam tests and characterization of irradiations by both conventional and FLASH proton beams. In these exploratory PET imaging and dosimetry studies, we demonstrate the feasibility of image guidance in proton therapy by exploiting the short-lived positron-emitting isotopes produced during beam irradiations. We also present ongoing detector R&D aimed at improving overall PET detector performance. These findings are meant to enable new protocols for treatment planning which can bring in-beam PET into the established treatment modalities.
| Field |
Detectors and electronics
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John Cesar
(The University of Texas at Austin)
Alex Kuo
(The University of Texas at Austin)
Andrey Morozov
(LIP)
Aryan Ojha
(The University of Texas at Austin)
Bruno Jesus
(University of Coimbra)
Carlos Leong
(PETsys Electronics)
David Grosshans
(M.D. Anderson Cancer Center)
Falk Poenisch
(M.D. Anderson Cancer Center)
Firas Abouzahr
(The University of Texas at Austin)
Francisco Caramelo
(University of Coimbra)
Hugo Simões
(LIP)
José Carlos Da Silva
(PETsys Electronics)
João Seco
(LIP)
João Varela
(LIP)
Karol Lang
(The University of Texas at Austin)
Kyle Klein
(The University of Texas at Austin)
Luís Ferramacho
(PETsys Electronics)
Marek Proga
(The University of Texas at Austin)
Margarida Simões
(LIP)
Michael Gajda
(The University of Texas at Austin)
Miguel Silveira
(PETsys Electronics)
Narayan Sahoo
(M.D. Anderson Cancer Center)
Nuño Ferreira
(University of Coimbra)
Patrícia Gonçalves
(LIP)
Paulo Crespo
(LIP, University of Coimbra)
Ricardo Bugalho
(PETsys Electronics)
Rui Francisco
(PETsys Electronics)
Rui Silva
(LIP)
Stefaan Tavernier
(PETsys Electronics, Vrije Universiteit Brussel)
Tiago Coutinho
(PETsys Electronics)
Vasco Varela
(PETsys Electronics)
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