Sahar Ranjbar
(Istituto Nazionale di Fisica Nucleare,University of Turin, Department of Physics, Torino, Italy)
The SIG (Superconducting Ion Gantry) project focuses on enhancing online monitoring performances of in-beam PET during ion treatments, developing new image reconstruction algorithms and analyses that consider fast-decaying isotope signals. In this study we presented the performance evaluation of an in-beam PET system for carbon ion irradiations. The Range Verification System prototype under investigation is based on state-of-the-art PET modules featuring segmented Luthetium Fine Silicate crystals coupled to Silicon Photomultiplier matrices. It was tested on carbon ion beams at two energies (144 MeV/u and 213 MeV/u) at the CNAO facility. The beams were impinging on homogeneous PMMA phantoms and data were acquired during the irradiation. The performance analysis was designed to evaluate the stability of range difference estimation considering several consecutive subsets of coincidence events with different event amounts. The range difference values were calculated between the two irradiated energies for each pair of images of the two energies from the subset lists. Our result indicates that the performance of the PET system appears to be minimally affected by the statistics included in the PET images and the average experimental range difference is compatible with the expected value. The obtained results are valuable for the ongoing design and implementation of a customized image reconstruction method focused on highlighting fast isotopes.
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Software and quantification
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Sahar Ranjbar
(Istituto Nazionale di Fisica Nucleare,University of Turin, Department of Physics, Torino, Italy)
Dr
Elisa Fiorina
(Istituto Nazionale di Fisica Nucleare,torino)
Dr
Francesco Pennazio
(Istituto Nazionale di Fisica NucleareTorino, Italy)
Dr
Felix Mas Milian
(Istituto Nazionale di Fisica Nucleare,State University of Santa Cruz, Ilhéus, BA, Brazil)
Anna Vignati
(Istituto Nazionale di Fisica Nucleare,University of Turin, Department of Physics, Torino, Italy)
Davide Bersani
(Istituto Nazionale di Fisica Nucleare)
Dr
Diango Manuel Montalvan Olivares
(Istituto Nazionale di Fisica Nucleare,University of Turin, Department of Physics, Torino, Italy)
Mr
Emanuele Maria Data
(Istituto Nazionale di Fisica Nucleare,University of Turin, Department of Physics, Torino, Italy)
Mr
Julius Friedemann Werner
(Institute of Medical Engineering, Universität zu Lübeck, Germany)
Marco Donetti
(Fondazione CNAO)
Marco Pullia
(CNAO)
Dr
Mohammad Adel Fadavi Mazinani
(Istituto Nazionale di Fisica NucleareTorino, Italy)
Dr
Mohammad Amin Hosseini
(Istituto Nazionale di Fisica Nucleare,University of Turin, Department of Physics, Torino, Italy)
Dr
Piergiorgio Cerello
(Istituto Nazionale di Fisica Nucleare)
Prof.
Roberto Cirio
(Istituto Nazionale di Fisica Nucleare,University of Turin, Department of Physics, Torino, Italy)
Prof.
Roberto Sacchi
(Istituto Nazionale di Fisica Nucleare,University of Turin, Department of Physics, Torino, Italy)
Dr
Simona Giordanengo
(Istituto Nazionale di Fisica Nucleare)
Dr
Veronica Ferrero
(Istituto Nazionale di Fisica Nucleare)
