Performance characteristics of multi-mouse imaging on monolithic large flat panel PET

22 May 2024, 16:00
5m
La Biodola, Isola d'Elba

La Biodola, Isola d'Elba

Hotel Hermitage
Poster High-performance preclinical and organ-specific systems Poster Session

Speaker

Meysam Dadgar

Description

This study introduces a novel small animal PET scanner aimed at overcoming limitations in preclinical imaging, specifically addressing the constraint of scanning a limited number of samples daily. The proposed scanner, featuring two flat panels with 16 BGO monolithic detectors each, demonstrates excellent spatial resolution (0.94 - 1.12 mm) with a 2mm depth of interaction (DOI) and high sensitivity (~38%). Capable of simultaneously imaging 12-60 mice, the scanner maintains spatial resolution across the entire imaging volume, making it a promising tool for high-population preclinical studies. The presented pre-clinical PET scanner significantly expedites small animal-based studies, offering researchers enhanced flexibility to include larger sample populations. With excellent system performance and the ability for multi-sample imaging, this advancement not only improves experimental efficiency but also broadens the potential insights derived from pre-clinical investigations.

Field Systems and applications

Primary author

Meysam Dadgar

Co-authors

Boris Vervenne (MEDISIP, Department of Electronics and Information Systems, Ghent University) stefaan vandenberghe (MEDISIP-IBBT-Ugent)

Presentation materials