PSMR2024 10th Conference on PET, SPECT, and MR Multimodal Technologies, Total Body and Fast Timing in Medical Imaging

openSSS: open-source custom geometry and total-body PET scatter correction

Not scheduled

20m

La Biodola, Isola d'Elba

Oral Total body imaging Total body PET imaging

Speaker

Rodrigo José Santo

Description

Scatter correction is essential for quantitative and accurate time-of-flight (TOF) PET imaging. However, scatter estimation algorithms for total body and other custom geometries are not available in open-source libraries. To this end, we have developed an open-source implementation of the TOF-aware single-scatter-simulation (SSS) algorithm (openSSS). It is validated on the NEMA phantom and the XCAT phantom, for conventional and custom geometries, compared to Monte-Carlo simulations and a vendor-specific reconstruction. A total-body scatter estimation is performed for the UI uEXPLORER geometry. The reconstructed images with openSSS scatter correction are visually similar with comparable contrast recovery. Feasibility of total-body scatter estimation is shown by analyzing the estimated scatter distributions. In conclusion, we have developed and validated an open-source TOF-aware SSS for use with reconstruction frameworks such as CASToR, compatible with custom and total-body scanner geometries.