IMAS: a total body PET with TOF and DOI capabilities

22 May 2024, 09:10
20m
La Biodola, Isola d'Elba

La Biodola, Isola d'Elba

Hotel Hermitage
Oral Total body imaging Technologies for total body PET imaging

Speaker

Antonio Gonzalez (Institute for Instrumentation in Molecular Imaging, i3M-CSIC)

Description

Total-Body PET (TB-PET) technology has become very popular in recent years. These systems are very attractive because of their high sensitivity, achieved through their extended axial field of view and, potentially, Time of Flight capabilities, allowing for the simultaneous study of the kinetics of multiple organs. Most of TB-PET designs are based on LYSO crystal pixels without DOI. In this work we present a TB-PET system based on semi-monolithic crystals and, therefore, simultaneously enabling TOF and depth of interaction capabilities. Our design, named IMAS, makes furthermore use of a reduction of signals without compromising performance. We first carried out exhaustive simulation studies of the system geometry, based on 5 rings of 10 cm in the axial direction each, and gaps of about 5 cm, with a total axial length of 71.4 cm. These studies confirm the good performance of the system in terms of spatial resolution, sensitivity and other relevant parameters. The system has been constructed and installed (June 2023) at the largest hospital in our region named La Fe. Very preliminary experimental tests, already predict an almost homogeneous spatial resolution below 4 mm in the whole FOV (as far as at 30 cm off-radial), outperforming any other scanner with a long axial FOV. The system sensitivity is 7.6% with a source at the Center of Field of View. The detectors reached a TOF of about 350 ps. We aim to report a full characterization of the scanner during the workshop.

Field Systems and applications

Primary authors

Antonio Gonzalez (Institute for Instrumentation in Molecular Imaging, i3M-CSIC) David Sanchez (Universidad Politécnica de Valencia) Dr Santiago Jimenez-Serrano (Institute for Instrumentation in Molecular Imaging, i3M-CSIC) Mr Alvaro Anreus (institute for Instrumentation in Molecular Imaging, i3M-CSIC) Mr Jorge Alamo (Oncovision) Mr Julio Barbera (Oncovision) Gabriel Cañizares (Universidad de Valencia) Ms Neus Cucarella (institute for Instrumentation in Molecular Imaging, i3M-CSIC) Marta Freire (Institute for Instrumentation in Molecular Imaging (i3m)) Andrea Gonzalez-Montoro (i3M-CSIC) Mr Constantino Morera (Oncovision) Dr Alfonso Rios (Full Body Insight) Dr Irene Torres (Hospital La Fe) Mr Luis F. Vidal (institute for Instrumentation in Molecular Imaging, i3M-CSIC) José María Benlloch Baviera (I3M-CSIC)

Presentation materials