Speaker
Description
Abstract—Pituitary adenomas, occurring in approximately 1 in 1100 individuals, can lead to a spectrum of symptoms by disrupting normal pituitary gland function, thereby significantly impacting quality of life. Positron emission tomography (PET) using [$^{11}$C]-methionine offers additional information in surgical planning, crucial for precise localisation of metabolically active pituitary adenomas, especially in smaller tumours where magnetic resonance imaging (MRI) alone may fail detecting such tumours. In this work we evaluate 3D variational regularisation using directional total variation (dTV) with different MRI-based structural information incorporated in PET reconstruction. The integration of structural details in PET reconstruction enhances image resolution, however, careful selection of anatomical information is essential to prevent structurally imposed PET distributions which are functionally improbable.
| Field | Systems and applications |
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