3D In-System Calibration of PET Detectors

21 May 2024, 16:50
20m
La Biodola, Isola d'Elba

La Biodola, Isola d'Elba

Hotel Hermitage
Oral Total body imaging AI enhanced PET detectors

Speaker

Yannick Kuhl (Department of Physics of Molecular Imaging Systems, Institute for Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany)

Description

In PET science, numerous high-performance detector designs are being investigated that are slowed in their system integration, e.g., due to a complex positioning calibration, including depth-of-interaction (DOI), required for several light-sharing designs. This process usually happens in benchtop setups, but a prerequisite for system integration is the fast acquisition of the training data for machine-learning applications and a practicable re-calibration and quality control.
We propose a new 3D in-system calibration with data acquisition inside the scanner by software-collimating a radioactive point source combined with angular detector irradiation for DOI. Experiments were conducted with a point source mounted to a 3-axis motor and placed inside a scanner dummy (120 mm diameter). The source was moved in front of a slab detector ((24 × 10 × 1) mm³ slabs). By selecting orthogonally incident gamma rays, a planar calibration was conducted using Gradient Tree Boosting. Then, the DOI was calibrated by selecting oblique angles and calculating the DOI label from the geometric ray path and the planar position estimate.
For planar positioning, the results were within 1% of state-of-the-art calibration at 0.8 mm MAE and 1.19 mm FWHM. For DOI, 1.13 mm MAE and 2.47 mm FWHM were achieved. The method’s applicability to different scanner geometries was analytically calculated and investigated.
The proposed in-system calibration method is suitable for 3D-calibrating assembled PET systems.

Field Systems and applications

Primary author

Yannick Kuhl (Department of Physics of Molecular Imaging Systems, Institute for Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany)

Co-authors

Dr Florian Müller (Department of Physics of Molecular Imaging Systems, Institute for Experimental Molecular Imaging, RWTH Aachen University) Julian Thull (Institute for Experimental Molecular Imaging, RWTH Aachen University) Stephan Niklas Naunheim (Department of Physics of Molecular Imaging Systems (PMI), Institute of Experimental Molecular Imaging (ExMI), RWTH Aachen University) Dr David Schug (Department of Physics of Molecular Imaging Systems, Institute for Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany) Prof. Volkmar Schulz (Department of Physics of Molecular Imaging, Institute of Experimental Molecular Imaging, RWTH-Aachen University)

Presentation materials