Speaker
Description
The brain of an in vivo rat has been imaged with 18F-Fluorodeoxyglucose (FDG) by means of the SAFIR-I PET insert, at injected activities of 29.6MBq and 314.6MBq. A measurement of a 50ml Falcon tube filled with a solution of FDG and water at 50MBq was used as approximate quantitative calibration of image voxel values. Based on the data, time-activity curves (TACs) have been generated for the cortex region and the whole brain at low and high decay rate. The curves are consistent with biological expectations. SAFIR-I could demonstrate its ability to acquire meaningful quantitative PET images at injected activities stretching beyond 300MBq. The accuracy of the TACs is still expected to improve with the inclusion of attenuation, random, normalization and scatter corrections, as well as quantitative calibration with a dedicated calibration phantom measurement at a comparable decay rate.
