28 May 2022 to 1 June 2022
La Biodola, Isola d'Elba
Europe/Rome timezone

The HYPMED PET/MRI Insert for Enhanced Diagnosis of Breast Cancer

29 May 2022, 09:30
20m
Maria Luisa

Maria Luisa

Oral PET/MR and SPECT/MR systems and applications PET/MR and SPECT/MR systems and applications

Speaker

Stephan Niklas Naunheim (Department of Physics of Molecular Imaging Systems (PMI), Institute of Experimental Molecular Imaging (ExMI), RWTH Aachen University)

Description

Addressing the increasing demands for improved cancer diagnosis and personalized medicine, the H2020 EU project HYPMED aims to develop a PET-RF insert, which is compatible to a 1.5T-MRI Philips Ingenia.
The insert targets the needs of enhanced breast cancer diagnosis, namely offering high-resolution imaging, increased systemsensitivity and also high system-integrity. The PET insert comprises two independent PET rings with a field of view (FOV) of 28 cm × 10 cm, as well as two dual-channel local receive coils. The mechanical designed allows the opening and closing of the PET rings, such that it is possible to perform biopsies without causing major effort and immobilize the breasts. Each PET ring utilizes 14×2 detector stacks comprising three-layered Lutetium–yttrium oxyorthosilicate (LYSO) crystal arrays with 1.3mm pitch. The MR-compatible detectors are based on the Hyperion III platform, using a sensor tile with 12×12 individual digital silicon photomultiplier (SiPM) channels (DPC-3200-22, Philips Digital Photon Counting) having a sensitive area of ∼48mm × 48mm each. The scintillator’s staggered design comprises 3425 crystals and allows the usage of depth of interaction (DOI) information, resulting in high and homogeneous spatial resolution across the FOVs.
We will present the first PET and MRI results of our system.

Primary author

Stephan Niklas Naunheim (Department of Physics of Molecular Imaging Systems (PMI), Institute of Experimental Molecular Imaging (ExMI), RWTH Aachen University)

Co-authors

Yannick Kuhl (RWTH Aachen University) Bjoern Weissler David Schug (1 Department of Physics of Molecular Imaging Systems, Institute for Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany 2 Hyperion Hybrid Imaging Systems GmbH, Aachen, Germany) Harald Radermacher (RWTH Aachen University) Florian Müller (Department of Physics of Molecular Imaging Systems, Institute for Experimental Molecular Imaging, RWTH Aachen University) Vanessa Nadig (RWTH Aachen University) Laiyin Yin (RWTH Aachen University) Karl Krueger Pierre Gebhardt (RWTH Aachen University) Nicolas Gross-Weege (Department of Physics of Molecular Imaging Systems, Institute for Experimental Molecular Imaging, RWTH Aachen University, Germany) Teresa Nolte (Philips Research Europe/RWTH Aachen) Eike Gegenmantel (Hyperion Hybrid Imaging Systems GmbH) Martino Borgo (Futura Composites) Jos van den Berghe (Futura Composites B.V., Heerhugowaard, The Netherlands) Daniel Gareis (NORAS MRI Products GmbH, Hoechberg, Germany) Turgay Celik (NORAS MRI Products GmbH, Hoechberg, Germany) André Salomon (Philips Research, Eindhoven, The Netherlands) Dennis Schaart (Delft University of Technology) Rene Bakker (Delft University of Technology, Delft, The Netherlands) Karl-Josef Langen (Forschungszentrum Juelich, Juelich, Germany) Christiane Kuhl (Department of Diagnostic and Interventional Radiology, University Hospital Aachen, Aachen, Germany) Volkmar Schulz (RWTH Aachen University, Hyperion Hybrid Imaging Systems, Fraunhofer MEVIS)

Presentation materials