Seminari Generali

Coherent diffraction, partial coherence and phase diversity

by Prof. Keith A Nugent (ARC Centre of Excellence for Coherent X-ray Science School of Physics, The University of Melbourne)

Europe/Rome
Aula Conversi (Dipartimento di Fisica - Ed. G. Marconi)

Aula Conversi

Dipartimento di Fisica - Ed. G. Marconi

Description
Coherent diffractive imaging (CDI) is a rapidly emerging area of research that is now beginning to see application to important problems in biology and materials science. In this talk I will review the historical development and current state of the field with a particular emphasis on work using synchrotron sources and free electron lasers. Modern X-ray lasers are not perfectly coherent and so I will also discuss the impact of the partial coherence of the light on the ability to reconstruct a reliable high-resolution image. In particular, I will discuss the work of my group in which we have measured the coherence properties and included them into the imaging process. I will also introduce the concept of phase-diversity in coherent X-ray imaging and I will present experimental data that I hope will convince you that coherent techniques are now able to produce very reliable high-resolution X-ray imaging of biological samples. An important potential application of CDI is to molecular imaging with a free electron laser. I will argue that the impact of the intense X-ray field on the molecule can be treated as a form of partial coherence and discuss how these ideas might ultimately be used to account for the effects of damage from the laser pulse and lead to reliable imaging of single molecules