Computational answers to experimental biophysics questions

by Emanuele Paci (Leeds university)

Friday 15 Jun 2018, 11:00 → 13:00 Europe/Rome

Aula Conversi (Dipartimento di Fisica - Ed. G.Marconi)

The fast development of advanced experimental probes, including single molecule ones, is revolutionising the study of complex biomolecular systems. Properties that have become measurable provide an opportunity to derive theories and models. I will show how computer simulations are valuable tools assess the validity of theories and the interpretability of experiments. I will present methods developed in my laboratory to answer questions raised by experiments and investigate structure and dynamics of proteins in different contexts, with a particular focus on single molecule force probes and mass spectrometry measurements.