Speaker
Gaspar Delso
(UniversitätsSpital Zürich)
Description
Pituitary tumours account for ~16% of central nervous system tumors and they are the second most frequently reported histology in this group. Due to their small size, pituitary surgery is challenging and precise lesion localization through imaging is therefore a critical factor for a successful outcome.
Simultaneous PET/MR is well suited for lesion identification and localization but it requires accurate attenuation correction to ensure optimal PET imaging. Atlas-based attenuation correction methods are often used for this purpose, as they overcome the difficulty of estimating bone tissue density with conventional MR sequences. However, atlas methods can only partially account for inter-patient variability.
The goal of the present study was to investigate whether direct bone measurement, by means of a zero echo time (ZTE) MR sequence, can significantly improve the accuracy of pituitary tumor imaging with PET.
Primary author
Gaspar Delso
(UniversitätsSpital Zürich)
Co-authors
Daniel Gillett
(Dept of Nuclear Medicine, Addenbrooke's Hospital, Cambridge, UK.)
Dr
Iosif Mendichovszky
(Dept of Nuclear Medicine, Addenbrooke's Hospital, Cambridge, UK.)
Dr
Mark Gurnell
(Institute of Metabolic Science, University of Cambridge & Addenbrooke's Hospital, Cambridge, UK.)
Dr
Tomasz Matys
(Dept of Radiology, Cambridge University, Cambridge, UK.)
Dr
Waiel Bashari
(Institute of Metabolic Science, University of Cambridge & Addenbrooke's Hospital, Cambridge, UK.)
