21–23 May 2018
La Biodola, Isola d'Elba
Europe/Rome timezone

Current status of the PET detector developments of a dedicated PET/MRI for the diagnosis of breast cancer

21 May 2018, 15:50
20m
Room Elena (Hotel Hermitage)

Room Elena

Hotel Hermitage

Speaker

Dr David Schug (RWTH Aachen University)

Description

Current clinical simultaneous PET/MRI systems as well as PET/CT systems have been designed as whole-body systems. In both hybrid modalities, PET is limited in spatial resolution and sensitivity. In particular, the low spatial resolution of PET limits the ability to detect cancer at early stages and to monitor therapy responses, develop/apply radiomics and radiogenomics methods. To overcome these limitations, we are developing a PET/MRI deployment in the EU H2020 HYPMED project that combines local MR receiver coils and local PET detectors. The aim is to achieve a homogeneous spatial resolution of about 1.2 mm (FWHM) with four times higher sensitivity than existing whole-body PET systems. The PET detector is based on Philips digital SiPMs and is designed to offer PET simultaneous with 1.5-T MRI scans of both breasts to limit the overall measurement time and effective use of the injected dose. We present the current state of the PET detector design of the breast PET /MRI system that we are developing in the HYPMED project. The insert includes a newly developed RF receiver coil and a highly integrated digital PET detector. The entire PET detector is a further development of our already developed HYPERION IID detector design. To support the clinical workflow, which includes the possibility of breast fixation and PET/MRI-guided biopsy, the PET detector offers the opportunity to open the two detector rings. To maintain a homogeneous spatial resolution, a three-layer DOI crystal design with 1-mm crystal pitch was examined, which shows an excellent separation of all three layers.

Primary author

Volkmar Schulz (RWTH Aachen University)

Co-authors

Dr Andre Salomon (Philips Research Eindhoven) Dr Bjoern Weissler (RWTH Aachen University) Mrs Christiane Kuhl (RWTH Aachen University) Dr David Schug (RWTH Aachen University) Dr Dennis Schaart (Delft University of Technology) Mr Dimitri Kuznetsov (Delft University of Technology) Dr Jeremy Brown (Delft University of Technology) Mr Jeroen Koeleman (Futura Composites B.V.) Mr K. A. Kamman (Delft University of Technology) Mr Layin Yin (RWTH Aachen University) Mr Marcel De Koning (Futura Composites B.V.) Dr Martino Borg (Futura Composites B.V.) Mr Nicolas Gross-Weege (RWTH Aachen University) Dr Pierre Gebhardt (RWTH Aachen University) Mr René Bakker (Delft University of Technology) Dr Sebastian Aussenhofer (Noras MRI Products) Mrs Teresa Nolte (RWTH Aachen University & Philips Research Eindhoven) Dr Thomas Dey (RWTH Aachen University) Mr Turgay Celik (Noras MRI Products)

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