Speaker
Antonio Gonzalez
(Institute for Instrumentation in Molecular Imaging, i3M-CSIC)
Description
We report in this work the current status performance of the brain PET insert developed under the MINDView project. Final construction has been accomplished. Pilot performance studies have been carried out at the lab, partially following the NEMA protocol. It has later been installed at the nuclear medicine department in Klinikum rechts der Isar (Munich) and exhaustively tested inside the Siemens mMR, a whole body PET-MR with a 3T main magnetic field. The PET insert FOV is 154 mm axially and 240 mm transaxially, defined by 3 rings of 20 monolithic crystals each (20 mm thick), coupled to custom 12x12 SiPM arrays. The system sensitivity is above 7% (350-650 keV) with a point-like source at the CFOV.
A variety of MR sequences for brain imaging have been run (EPI, ASL, T1w, T2w and UTE), and the PET response measured, without showing any deterioration. Count rates as a function of sequences were studied not also exhibiting a system malfunction. Also the MR performance has been studied, among other tests the uniformity of the B0 and B1 fields, not showing significant changes when the dedicated brain PET is inserted.
Regarding performance comparison with a state-of-the-art whole body PET system, it shows an improved performance as observed through the mini-Derenzo or other phantoms. Rods of about 2 mm are clearly distinguished with standard iterative reconstruction methods and voxel/pixel sizes.
Detailed analyses will be presented. Currently, the system is in Klinikum rechts der Isar (Munich) and patients recruitment is undergoing.
Primary author
Antonio Gonzalez
(Institute for Instrumentation in Molecular Imaging, i3M-CSIC)
Co-authors
Dr
Amadeo Iborra
(Brest University)
Ms
Andrea Gonzalez-Montoro
(i3M-CSIC)
Mr
Carlos Correcher
(Bruker Biospin)
Prof.
Dimitris Visvikis
(INSERM)
Mr
Edwin J. Pincay
(Institute for Instrumentation in Molecular Imaging)
Mr
Efthymios Lamprou
(Institute for Instrumentation in Molecular Imaging)
Dr
Filomeno Sanchez
(Institute for Instrumentation in Molecular Imaging)
Mr
Gabriel Cañizares
(Universidad de Valencia)
Dr
Jorge Cabello
(Klinikum rechts der Isar (TUM))
Mr
José María Benlloch Baviera
(I3M-CSIC)
Mr
Juan V. Catret
(Oncovision)
Mr
Julio Barbera
(Oncovision)
Ms
Laura Moliner
(Institute of Instrumentation for Molecular Imaging - CSIC)
Mr
Luis F. Vidal
(Institute for Instrumentation in Molecular Imaging)
Prof.
Markus Schwaiger
(TUM)
Mr
Santiago Jimenez
(Oncovision)
Dr
Sebastian Aussenhofer
(Noras)
Mr
Sebastian Sanchez Goez
(student)
Dr
Thibaut Merlin
(Brest University)
