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SUMMARY:Copper radioisotopes production for nuclear medicine applications:
  my experience at University of Wisconsin-Madison (USA)
DTSTART:20260126T100000Z
DTEND:20260126T120000Z
DTSTAMP:20260507T133000Z
UID:indico-event-50000@agenda.infn.it
CONTACT:sara.cisternino@lnl.infn.it
DESCRIPTION:Speakers: Gaja Piteo (INFN - LNL)\n\nRadiopharmaceuticals are 
 widely used tools in advanced nuclear medicine aimed at the diagnosis and 
 treatment of both oncological and non-oncological diseases. Depending upon
  the type of radiation emitted by the radionuclide concerned\, they can be
  used for either diagnostic imaging (SPECT or PET) and targeted therapy. I
 n recent years\, the theranostic approach has emerged\, combining diagnosi
 s and treatment by using theranostic radionuclides (or radionuclide pairs)
  labelled with the same or closely related molecules\, thus opening new ro
 utes for personalized therapies. Among them\, copper radionuclides have sh
 own a growing interest worldwide\, mainly due to their peculiar β-\, elec
 tron capture\, and positron decays combined features. Specific (i.e.\, β-
  and Auger electrons) emissions aimed at therapy as well as gamma rays emi
 ssions (following β- or positron decays) exploited for tomographic imagin
 g may therefore be applied. Radionuclides of interests (mainly radiometals
 ) can be produced either in a nuclear fission reactor or by using cyclotro
 ns coupled with different solid targets (Ni\, Zn\, Cu and Co). However\, t
 he matter of selecting the starting material combined with the target manu
 facturing procedure may markedly affect the final radionuclidic purity\, r
 adiochemical quality\, as well as yield\, specific activity\, and the effi
 ciency of target material recovery. In this seminar\, I will present my Ph
 .D. research activity carried out during my period abroad at the Universit
 y of Wisconsin-Madison (USA)\, within the framework of a collaborative pro
 ject with the LARAMED group. The results obtained from different methods o
 f producing copper radioisotopes through direct activation by cyclotron ir
 radiation of solid targets will be presented. A focus will be placed on th
 e comparison between the new spark plasma sintering process for target pro
 duction with the established standard technique of electrodeposition\, as 
 well as the evaluation of effects of different starting materials on the q
 uality of the final product.\nLink Zoomhttps://infn-it.zoom.us/j/838698862
 00?pwd=mb484LIw21vctPGeiA8Rs03ehj6qIg.1ID riunione: 838 6988 6200Codice d
 ’accesso: 730366\n\nhttps://agenda.infn.it/event/50000/
LOCATION:M.B. Ceolin meeting room
URL:https://agenda.infn.it/event/50000/
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