Speaker
Summary
The demand for positron emission tomography (PET) isotopes like gallium-68 (68Ga) and zirconium-89 (89Zr) has significantly increased due to their crucial role in diagnostic imaging and targeted radiopharmaceutical therapies. 68Ga is widely used for PET imaging of neuroendocrine and prostate tumors, while 89Zr is ideal for immunoPET applications due to its longer half-life, making it suitable for antibody-based imaging. Recent technological advancements have enabled more efficient and reliable isotope production systems, with a focus on automation and integrated solutions. This study presents the combined use of the Alceo (Comecer) and Synthera (IBA) systems for streamlined, high-purity production of 68Ga and 89Zr, aiming to improve yield, reduce manual intervention, and enhance reproducibility in radiopharmaceutical manufacturing.