Feb 15 – 19, 2026
Grand Hotel Mediterraneo
Europe/Rome timezone
12th International Conference on Isotopes - 12ICI

TOWARDS RADIONUCLIDICALLY PURE N.C.A. Ho-166 VIA AN INDIRECT REACTOR PRODUCTION ROUTE FOR THERAPEUTIC APPLICATIONS

Feb 17, 2026, 3:14 PM
15m
Plenaria: Africa Room (Grand Hotel Mediterraneo)

Plenaria: Africa Room

Grand Hotel Mediterraneo

Oral presentation 1. Isotopes Production and Devices 1. Isotopes Production and Devices - Tue_S2_A

Speaker

Edoardo Renaldin (Paul Scherrer Institute)

Summary

166Ho is a promising therapeutic radionuclide thanks to its high-energy β⁻ emissions, but clinical supplies are typically carrier-added and direct production co-generates long-lived 166mHo. We address this by pursuing an indirect route: irradiating enriched 164Dy₂O₃ to enable large-scale production of non-carrier-added 166Ho without 166mHo. This strategy also supports a practical generator concept.

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Author

Edoardo Renaldin (Paul Scherrer Institute)

Co-authors

Mr Chen Yan (University of Bern) Nick van der Meulen (Paul Scherrer Institute) Prof. Robert Eichler (Paul Scherrer Institute) Ulli Köster (Institut Laue Langevin) Zeynep Talip (Paul Scherrer Institute)

Presentation materials

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