Feb 15 – 19, 2026
Grand Hotel Mediterraneo
Europe/Rome timezone
12th International Conference on Isotopes - 12ICI

OPTIMIZATION AND VALIDATION OF THE INDIRECT Tb-155 PRODUCTION ROUTE IN THE APHRODITE-155 PROJECT

Feb 17, 2026, 3:30 PM
15m
Plenaria: Asia Room (Grand Hotel Mediterraneo)

Plenaria: Asia Room

Grand Hotel Mediterraneo

Oral presentation 1. Isotopes Production and Devices 1. Isotopes Production and Devices - Tue_S2_B

Speaker

Michele Colucci (Istituto Nazionale di Fisica Nucleare)

Summary

Terbium radionuclides are emerging as key isotopes for theranostic applications, offering matched pairs for imaging and therapy. Among them, 155Tb is a promising SPECT radionuclide suitable for dosimetric validation of therapeutic analogues such as 161Tb and ¹⁷⁷Lu. Its routine production, however, remains challenging due to limited yields from direct reactions and the scarcity of enriched target material. The APHRODITE-155 project explores an indirect production route based on the decay of 155Dy obtained through 159Tb(p,x) nuclear reactions, integrating nuclear data acquisition, process modeling, and radiochemical separation optimization.

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Author

Michele Colucci (Istituto Nazionale di Fisica Nucleare)

Co-authors

Arnaud GUERTIN (CNRS/IN2P3/SUBATECH) Etienne NIGRON (GIP ARRONAX) Ferid Haddad Flavia Maria Groppi (Istituto Nazionale di Fisica Nucleare) Nadia Audouin (GIP Arronax) Simone Manenti (Department of Physics, University of Milan) Thomas Sounalet (Subatech)

Presentation materials

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