Toward the prediction of the absolute quality of single protein structure models

by Dr Pascal Benkert (Swiss Institute of Bioinformatics, University of Basel)

Monday 14 Feb 2011, 11:15 → 13:00 Europe/Rome

Aula Conversi (Dip. di Fisica - Edificio G. Marconi)

Estimating the quality of predicted structural models is a vital step in homology modeling since the individual models may contain considerable errors. The talk provides an introduction to model quality assessment with an overview on different categories of methods and current challenges in the field. Then, the composite scoring function QMEAN based on statistical potentials is introduced.