Recently, some deviations with respect to Standard Model predictions in rare B-meson decays have been measured by the LHCb experiment. These deviations consist of angular observables in the $B^0\to K^*\mu^+\mu^-$ decay, branching ratio measurements of $b\to s\mu^+ \mu^-$ transitions and the ratio of the branching ratios $R_K=\frac{B^+\to K^+\mu^+\mu^-}{B^+\to K^+ e^+ e^-}$. Intriguingly, these anomalies seem to form a coherent pattern. I will discuss the experimental measurements of these observables and their interpretation, including theory uncertainties and future prospects. Finally, I will present measurements of the ratio of the branching ratio of the decays $B\to D^{(*)} \tau \nu$ and $B\to D^{(*)} \mu \nu$, which show significant deviations from lepton universality and Standard Model predictions. I will discuss the experimental measurements by BaBar, Belle and LHCb and future prospects.