Meeting 2016 Biophys & Pieces

Session

Sessione 7

Sep 28, 2016, 9:30 AM

Conveners

Sessione 7

• Giuseppe Gonnella (BA)

26. Computer-Aided Protein Engineering: Hemolysin and Ferritin as Test Cases

Prof. Giuseppe Brancato (SNS Pisa)

9/28/16, 9:30 AM

TBA

27. Application of Simulation Methodologies to Investigate the Structural Dynamics of Biological Channels.

Dr Balasubramanian Chandramouli (SNS Pisa)

9/28/16, 9:50 AM

TBA

11. Stochastic Model of Supercoiling-Dependent Transcription

Mr Alessandro Bentivoglio (Università degli Studi di Bari)

9/28/16, 10:20 AM

We propose a stochastic model for gene transcription coupled to DNA supercoiling, where we incorporate the experimental observation that polymerases create supercoiling as they unwind the DNA helix and that these enzymes bind more favorably to regions where the genome is unwound. Within this model, we show that when the transcriptionally induced flux of supercoiling increases, there is a...

4. Evolution of transcription factor families along the human lineage.

Antonio Rosanova (T)

9/28/16, 10:40 AM

Transcription factors (TFs) exert their regulatory action by binding to DNA with specific sequence preferences. However, different TFs can partially share their binding sequences. This ``redundancy'' of binding defines a way of organizing TFs in ``motif families'' that goes beyond the usual classification based on protein structural similarities. Since the TF binding preferences ultimately...